[HTML][HTML] Novel insights into the roles of N6-methyladenosine (m6A) modification and autophagy in human diseases
J Liang, J Sun, W Zhang, X Wang, Y Xu… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Autophagy is an evolutionarily conserved cellular degradation and recycling process. It is
important for maintaining vital cellular function and metabolism. Abnormal autophagy activity …
important for maintaining vital cellular function and metabolism. Abnormal autophagy activity …
Insulin-like growth factor 2 mRNA-binding protein 2—A potential link between type 2 diabetes mellitus and cancer
J Cao, W Yan, X Ma, H Huang… - The journal of clinical …, 2021 - academic.oup.com
Context Type 2 diabetes mellitus (T2DM) and cancer share a variety of risk factors and
pathophysiological features. It is becoming increasingly accepted that the 2 diseases are …
pathophysiological features. It is becoming increasingly accepted that the 2 diseases are …
[HTML][HTML] Interactions between long non‑coding RNAs and RNA‑binding proteins in cancer
H Huang, L Li, K Wen - Oncology reports, 2021 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) fulfill important roles in the majority of cellular processes.
Previous studies have demonstrated that lncRNAs are involved in the pathogenesis of …
Previous studies have demonstrated that lncRNAs are involved in the pathogenesis of …
[HTML][HTML] The m6A-related long noncoding RNA signature predicts prognosis and indicates tumor immune infiltration in ovarian cancer
R Geng, T Chen, Z Zhong, S Ni, J Bai, J Liu - Cancers, 2022 - mdpi.com
Simple Summary OV is the most lethal gynecological malignancy. M6A and lncRNAs have a
great impact on OV development and patient immunotherapy response. This study provided …
great impact on OV development and patient immunotherapy response. This study provided …
[HTML][HTML] Reprogramming of central carbon metabolism in hepatocellular carcinoma
H Xia, Z Huang, Y Xu, JWP Yam, Y Cui - Biomedicine & Pharmacotherapy, 2022 - Elsevier
In multicellular organisms, nutrient uptake and its metabolism are subject to stringent
regulation to maintain cellular integrity and prevent aberrant cell proliferation. However, the …
regulation to maintain cellular integrity and prevent aberrant cell proliferation. However, the …
[HTML][HTML] N6-methyladenosine (m6A) in pancreatic cancer: Regulatory mechanisms and future direction
J Li, F Wang, Y Liu, H Wang, B Ni - International Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract N 6-methyladenosine (m 6 A), the most abundant RNA modification in eukaryotes,
plays a pivotal role in regulating many cellular and biological processes. Aberrant m 6 A …
plays a pivotal role in regulating many cellular and biological processes. Aberrant m 6 A …
[HTML][HTML] LCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis
J Yang, X Qian, Q Qiu, L Xu, M Pan, J Li, J Ren… - Cell Death & …, 2022 - nature.com
Long non-coding RNAs (lncRNAs) is known to play vital roles in modulating tumorigenesis.
We previously reported that LCAT1, a novel lncRNA, promotes the growth and metastasis of …
We previously reported that LCAT1, a novel lncRNA, promotes the growth and metastasis of …
METTL3-Mediated lncRNA m6A Modification in the Osteogenic Differentiation of Human Adipose-Derived Stem Cells Induced by NEL-Like 1 Protein
Y Song, Y Pan, M Wu, W Sun, L Luo, Z Zhao… - Stem Cell Reviews and …, 2021 - Springer
Objectives This study aimed to explore the regulatory mechanism of methyltransferase3
(METTL3)-mediated long non-coding RNA (lncRNA) N6-methyladenosine (m 6 A) …
(METTL3)-mediated long non-coding RNA (lncRNA) N6-methyladenosine (m 6 A) …
[HTML][HTML] Long noncoding RNA KCNQ1OT1 promotes colorectal carcinogenesis by enhancing aerobic glycolysis via hexokinase-2
C Chen, M Wei, C Wang, D Sun, P Liu, X Zhong… - Aging (albany …, 2020 - ncbi.nlm.nih.gov
In this study, we investigated the mechanistic role and prognostic significance of the long
coding RNA (lncRNA) KCNQ1OT1 in colorectal cancer (CRC). KCNQ1OT1 levels were …
coding RNA (lncRNA) KCNQ1OT1 in colorectal cancer (CRC). KCNQ1OT1 levels were …
The emerging clinical application of m6A RNA modification in inflammatory bowel disease and its associated colorectal cancer
X Xu, J Huang, DKW Ocansey, Y Xia… - Journal of …, 2021 - Taylor & Francis
Methylation, first proposed in DNAs, but later found in RNAs, serves as one of the most
widespread epigenetic modifications in eukaryotes, where N6-methyladenosine (m6A) …
widespread epigenetic modifications in eukaryotes, where N6-methyladenosine (m6A) …