[HTML][HTML] The roles of KLHL family members in human cancers

G Ye, J Wang, W Yang, J Li, M Ye… - American Journal of …, 2022 - ncbi.nlm.nih.gov
The Kelch-like (KLHL) family members consist of three domains: bric-a-brac, tramtrack,
broad complex/poxvirus and zinc finger domain, BACK domain and Kelch domain, which …

Upregulation of KLHL17 promotes the proliferation and migration of non-small cell lung cancer by activating the Ras/MAPK signaling pathway

Z Liu, M Zhao, X Jiang, Y Zhang, S Zhang, Y Xu… - Laboratory …, 2022 - nature.com
Abstract Analysis of the Gene Expression Profiling Interactive Analysis (GEPIA) database
revealed that Kelch-like 17 (KLHL17) is overexpressed in non-small cell lung cancer …

[HTML][HTML] Characterization of KLHL14 anti-oncogenic action in malignant mesothelioma

A Canciello, RB Domínguez, B Barboni, A Giordano… - Heliyon, 2024 - cell.com
Malignant mesothelioma (MM) is a very aggressive neoplasia with a short life expectancy
and limited therapeutic options. Thus, the identification of novel molecular targets is a matter …

KLHL14: a novel prognostic biomarker and therapeutic target for ovarian cancer

X Wang, R Sun, X Hong, C Chen, Y Ding - Journal of Oncology, 2022 - Wiley Online Library
Ovarian cancer (OV) is a gynaecological malignancy that poses a serious risk to the health
status of women. To date, effective molecular markers are unavailable for the diagnosis and …

Prognostic biomarker-based identification of drugs for managing the treatment of endometrial cancer

D Kaur, C Arora, GPS Raghava - Molecular Diagnosis & Therapy, 2021 - Springer
Introduction Uterine corpus endometrial carcinoma (UCEC) causes thousands of deaths per
year. To improve the overall survival of patients with UCEC, there is a need to identify …

[HTML][HTML] Kelch-like protein 14 promotes proliferation and migration of ovarian cancer cells

Z Chen, M Wu, J Liu - International Journal of Clinical and …, 2020 - ncbi.nlm.nih.gov
Abstract Kelch-like protein 14 (KLHL14) belongs to the Kelch gene family, which interacts
with TorsinA and is associated with dystonia symptoms. However, the effect of KLHL14 on …

KLHL7 在非小细胞肺癌中的表达及其临床意义

黄庭, 贡会源, 唐震, 李伟, 张雷, 李小军, 高雄 - 中华全科医学, 2023 - zhqkyx.net
目的探讨非小细胞肺癌(NSCLC) 组织及癌旁组织中Kelch 样家族成员7 (KLHL7)
的表达情况与NSCLC 患者预后的相关性. 方法运用TIMER, UALCAN 数据库分析KLHL7 …

Pattern recognition receptor based prognostic biomarkers for predicting survival of uterine corpus endometrial cancer patients

D Kaur, C Arora, GPS Raghava - bioRxiv, 2020 - biorxiv.org
In this study, we attempted to identify prognostic biomarkers for predicting survival risk of
uterine corpus endometrial cancer (UCEC) patients from the gene expression profile of …