Usual interstitial pneumonia as a stand-alone diagnostic entity: the case for a paradigm shift?

M Selman, A Pardo, AU Wells - The Lancet Respiratory Medicine, 2023 - thelancet.com
Usual interstitial pneumonia (UIP) is characterised by a distinctive morphological and
radiological appearance that was considered the pathognomonic hallmark of idiopathic …

[HTML][HTML] Understanding interstitial lung diseases associated with connective tissue disease (CTD-ILD): genetics, cellular pathophysiology, and biologic drivers

G Cerro Chiang, T Parimon - International journal of molecular sciences, 2023 - mdpi.com
Connective tissue disease-associated interstitial lung disease (CTD-ILD) is a collection of
systemic autoimmune disorders resulting in lung interstitial abnormalities or lung fibrosis …

[HTML][HTML] A review of Janus kinase inhibitors for the treatment of Covid-19 pneumonia

Y Tanaka - Inflammation and Regeneration, 2023 - Springer
Background In inflamed tissue, immune cells are accumulated, and various intercellular
signals are involved in the pathogenesis. Janus kinases (JAKs) are typical tyrosine kinases …

[HTML][HTML] Etiology and Pathogenesis of Rheumatoid Arthritis-Interstitial Lung Disease

Y Kim, HI Yang, KS Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Interstitial lung disease (ILD) is one of the most serious extra-articular complications of
rheumatoid arthritis (RA), which increases the mortality of RA. Because the pathogenesis of …

[HTML][HTML] Unmet needs and perspectives in rheumatoid arthritis-associated interstitial lung disease: A critical review

A Stainer, A Tonutti, M De Santis, F Amati… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
synovitis as the most common clinical manifestation, and interstitial lung disease (RA-ILD) …

[HTML][HTML] Интерстициальные заболевания легких при ревматоидном артрите: мультидисциплинарная проблема ревматологии и пульмонологии

ЕЛ Насонов, ЛП Ананьева… - Научно-практическая …, 2022 - cyberleninka.ru
Ревматоидный артрит (РА)-иммуновоспалительное ревматическое заболевание
(ИВРЗ), характеризующееся хроническим эрозивным артритом и системным …

[HTML][HTML] Tofacitinib in the treatment of primary Sjögren's syndrome-associated interstitial lung disease: study protocol for a prospective, randomized, controlled and …

R Gao, J Pu, Y Wang, Z Wu, Y Liang, J Song… - BMC Pulmonary …, 2023 - Springer
Introduction Tofacitinib, a selective inhibitor of JAK1 and/or JAK3, is considered to alleviate
the pulmonary condition of primary Sjögren's syndrome (pSS)-associated interstitial lung …

[HTML][HTML] The usual Interstitial pneumonia pattern in autoimmune rheumatic diseases

F Luppi, A Manfredi, P Faverio, MB Andersen… - BMC Pulmonary …, 2023 - Springer
Abstract Usual Interstitial Pneumonia (UIP) is characterized by progression of lung
parenchyma that may be observed in various autoimmune rheumatic diseases (ARDs) …

[HTML][HTML] Transcriptomic and network analysis identifies shared and unique pathways and immune changes across fibrotic interstitial lung diseases

W Liu, K Huang, XZ Yang, P Wang - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: Interstitial lung disease (ILD) encompasses a diverse group of disorders
characterized by chronic inflammation and fibrosis of the pulmonary interstitium. Three ILDs …

Noncanonical JAK1/STAT3 interactions with TGF-β modulate myofibroblast transdifferentiation and fibrosis

F Wang, S Wang, C Zhang, X Tian… - … of Physiology-Lung …, 2022 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited survival. Janus
kinases (JAKs), tyrosine kinases that transduce cytokine-mediated signals, are known to be …