Implant surface design has evolved to meet oral rehabilitation challenges in both healthy
and compromised bone. For example, to conquer the most common dental implant-related …

Osteoporosis is defined as a systemic skeletal disease characterized by decreased bone
mass and micro-architectural deterioration leading to increased fracture risk. Osteoporosis …

Closed circulatory systems underlie the function of vertebrate organs, but in long bones their
structure is unclear although they constitute the exit route for bone marrow (BM) leukocytes …

Bone metastases are frequently the final fate of breast and prostate cancer patients.
According to the definition of metastasis as an incurable disease, to date there are no …

Osteoporosis is the most common disease involving bone degeneration. Current clinical
treatments are not able to offer a satisfying curative effect, so the development of effective …

Historically, the main classes of drug targets have been receptors, enzymes, ion channels
and transporters. However, owing largely to the rise of antibody-based therapies in the past …

Osteoporosis is a highly prevalent disorder characterized by the loss of bone mass and
microarchitecture deterioration of bone tissue, attributed to various factors, including …

Bone is organized in a hierarchical 3D architecture. Traditionally, analysis of the skeletal
system was based on bone mass assessment by radiographic methods or on the …

New anti-osteoporotic agents have been developed, potentially enriching the therapeutic
armamentarium. Currently available osteoanabolic therapies are the parathyroid hormone …

Magnesium (Mg) is a potential biomaterial suitable for developing biodegradable
orthopaedic implants, especially as internal fixators for fracture fixation at non-load bearing …