The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications

DB Kell, GJ Laubscher, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …

[HTML][HTML] The lactate and the lactate dehydrogenase in inflammatory diseases and major risk factors in COVID-19 patients

GS Gupta - Inflammation, 2022 - Springer
Lactate dehydrogenase (LDH) is a terminating enzyme in the metabolic pathway of
anaerobic glycolysis with end product of lactate from glucose. The lactate formation is crucial …

[HTML][HTML] COVID-19-associated candidiasis: possible patho-mechanism, predisposing factors, and prevention strategies

N Ahmed, MS Mahmood, MA Ullah, Y Araf… - Current …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is threatening public health. A large number of …

[HTML][HTML] SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry

O Matveeva, Y Nechipurenko, D Lagutkin… - Frontiers in …, 2022 - frontiersin.org
Our review summarizes the evidence that COVID-19 can be complicated by SARS-CoV-2
infection of immune cells. This evidence is widespread and accumulating at an increasing …

Potential of omega 3 supplementation for coronavirus disease 2019 (COVID-19): a scoping review

N Nursyifa Fadiyah, G Megawati… - … journal of general …, 2022 - Taylor & Francis
COVID-19 can cause fever, cough, headache, and shortness of breath but patients with
comorbidities can experience worsening and death. An action is needed to treat this …

[HTML][HTML] COVID-19-associated fungal infections in Iran: A systematic review

T Nazari, F Sadeghi, A Izadi, S Sameni, S Mahmoudi - PLoS One, 2022 - journals.plos.org
Objectives This systematic review aims to summarize the mycological and clinical features of
COVID-19-associated fungal infections (CAFIs) in Iran. Methods PubMed, Web of Science …

[HTML][HTML] High-dose vitamin D supplementation is related to an improvement in serum alkaline phosphatase in COVID-19 patients; a randomized double-blinded …

RR Moghaddam, Z Khorasanchi, AR Noor… - Journal of Health …, 2023 - Springer
Background The benefits and harms of vitamin D supplementation in the treatment of COVID-
19 have not yet been fully documented. In this study, we aimed to evaluate the effects of high …

[HTML][HTML] The use of the statistical entropy in some new approaches for the description of biosystems

VV Aristov, AS Buchelnikov, YD Nechipurenko - Entropy, 2022 - mdpi.com
Some problems of describing biological systems with the use of entropy as a measure of the
complexity of these systems are considered. Entropy is studied both for the organism as a …

[HTML][HTML] Hypothesis: inflammatory acid-base disruption underpins Long Covid

V van der Togt, JS Rossman - Frontiers in Immunology, 2023 - frontiersin.org
The mechanism of Long Covid (Post-Acute Sequelae of COVID-19; PASC) is currently
unknown, with no validated diagnostics or therapeutics. SARS-CoV-2 can cause …