Deep brain stimulation (DBS) has emerged as a promising treatment for select patients with
refractory major depressive disorder (MDD). The clinical effectiveness of DBS for MDD has …

Despite a growing neuroimaging literature on the pathophysiology of major depressive
disorder (MDD), reproducible findings are lacking, probably reflecting mostly small sample …

Background Establishing objective and quantitative neuroimaging biomarkers at individual
level can assist in early and accurate diagnosis of major depressive disorder (MDD) …

Major depressive disorder (MDD) is characterized by impairments in mood and cognitive
functioning, and it is a prominent source of global disability and stress. A functional magnetic …

Abstract Background and Hypothesis Dynamics of the distributed sets of functionally
synchronized brain regions, known as large-scale networks, are essential for the emotional …

Background Late-life depression (LLD) is a common and serious mental disorder, whose
neural mechanisms are not yet fully understood. In this study, we aimed to characterize LLD …

Recent studies have shown that major depressive disorder (MDD) is accompanied by
alterations in functional and structural network gradients. However, whether changes are …

Childhood trauma is a leading risk factor for adolescents developing major depressive
disorder (MDD); however, the underlying neuroimaging mechanisms remain unclear. This …

Phenotyping approaches grounded in structural network science can offer insights into the
neurobiological substrates of psychiatric diseases, but this remains to be clarified at the …

BackgroundExploring the neural basis related to different mood states is a critical issue for
understanding the pathophysiology underlying mood switching in bipolar disorder (BD), but …