The 2022 report on the human proteome from the HUPO human proteome project

GS Omenn, L Lane, CM Overall, C Pineau… - Journal of proteome …, 2022 - ACS Publications
The 2022 Metrics of the Human Proteome from the HUPO Human Proteome Project (HPP)
show that protein expression has now been credibly detected (neXtProt PE1 level) for 18 …

Clinical applications of plasma proteomics and peptidomics: Towards precision medicine

B He, Z Huang, C Huang… - PROTEOMICS–Clinical …, 2022 - Wiley Online Library
In the context of precision medicine, disease treatment requires individualized strategies
based on the underlying molecular characteristics to overcome therapeutic challenges …

Towards precision medicine: Omics approach for COVID-19

X Cen, F Wang, X Huang, D Jovic, F Dubee… - Biosafety and …, 2023 - mednexus.org
The coronavirus disease 2019 (COVID-19) pandemic had a devastating impact on human
society. Beginning with genome surveillance of severe acute respiratory syndrome …

Plasma markers of COVID-19 severity: a pilot study

J Beimdiek, S Janciauskiene, S Wrenger, S Volland… - Respiratory …, 2022 - Springer
Background SARS-CoV-2 infected patients show heterogeneous clinical presentations
ranging from mild symptoms to severe respiratory failure and death. Consequently, various …

A two-gene marker for the two-tiered innate immune response in COVID-19 patients

H Lei - PLoS One, 2023 - journals.plos.org
For coronavirus disease 2019 (COVID-19), a pandemic disease characterized by strong
immune dysregulation in severe patients, convenient and efficient monitoring of the host …

Fetuin‐A, inter‐α‐trypsin inhibitor, glutamic acid and ChoE (18: 0) are key biomarkers in a panel distinguishing mild from critical coronavirus disease 2019 outcomes

L Reverté, E Yeregui, M Olona… - Clinical and …, 2022 - Wiley Online Library
Dear Editor, The mechanistic pathways leading to immune dysregulation and complications
driven by uncontrolled severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

Identification of SARS-CoV-2 proteins from nasopharyngeal swabs probed by multiple reaction monitoring Tandem Mass Spectrometry

G Pinto, A Illiano, V Ferrucci, F Quarantelli… - ACS …, 2021 - ACS Publications
Numerous reverse transcription polymerase chain reaction (RT-PCR) tests have emerged
over the past year as the gold standard for detecting millions of cases of SARS-CoV-2 …

Integrative multi-omics approach for identifying molecular signatures and pathways and deriving and validating molecular scores for COVID-19 severity and status

D Lipman, SE Safo, T Chekouo - BMC genomics, 2023 - Springer
Background There is still more to learn about the pathobiology of COVID-19. A multi-omic
approach offers a holistic view to better understand the mechanisms of COVID-19. We used …

The serum of COVID-19 asymptomatic patients up-regulates proteins related to endothelial dysfunction and viral response in circulating angiogenic cells ex-vivo

L Beltrán-Camacho, S Eslava-Alcón, M Rojas-Torres… - Molecular …, 2022 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already
caused 6 million deaths worldwide. While asymptomatic individuals are responsible of many …

Proteomic profiling identifies biomarkers of COVID-19 severity

NC Harriott, AL Ryan - Heliyon, 2024 - cell.com
SARS-CoV-2 infection remains a major public health concern, particularly for the aged and
those individuals with co-morbidities at risk for developing severe COVID-19. Understanding …