The role, mechanism, and application of RNA methyltransferase METTL14 in gastrointestinal cancer
B Shi, WW Liu, K Yang, GM Jiang, H Wang - Molecular cancer, 2022 - Springer
Gastrointestinal cancer is the most common human malignancy characterized by high
lethality and poor prognosis. Emerging evidences indicate that N6-methyladenosine (m6A) …
lethality and poor prognosis. Emerging evidences indicate that N6-methyladenosine (m6A) …
N6-methyladenosine-modified circular RNA QSOX1 promotes colorectal cancer resistance to anti-CTLA-4 therapy through induction of intratumoral regulatory T cells
Z Liu, N Zheng, J Li, C Li, D Zheng, X Jiang, X Ge… - Drug Resistance …, 2022 - Elsevier
Background Colorectal cancer (CRC) is the 3rd most common cancer worldwide. CircRNAs
are promising novel biomarkers for CRC. T regulatory (Treg) cells express the immune …
are promising novel biomarkers for CRC. T regulatory (Treg) cells express the immune …
[HTML][HTML] N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization
Tumor metastasis is the leading cause of death in patients with colorectal cancer (CRC).
Circular RNAs (circRNAs) have been shown to be involved in cancer progression. However …
Circular RNAs (circRNAs) have been shown to be involved in cancer progression. However …
m6A modification on the fate of colorectal cancer: functions and mechanisms of cell proliferation and tumorigenesis
X Jiang, Z Jin, Y Yang, X Zheng, S Chen… - Frontiers in …, 2023 - frontiersin.org
N6-methyladenosine (m6A) is the most pervasive RNA modification in eukaryotic cells. The
dynamic and reversible m6A modification of RNA plays a critical role in the occurrence and …
dynamic and reversible m6A modification of RNA plays a critical role in the occurrence and …
[HTML][HTML] Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m6A signaling
K Sun, Y Du, Y Hou, M Zhao, J Li, Y Du, L Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Purpose: The implementation of targeted therapies for acute myeloid leukemia (AML) has
been challenging. Fat mass and obesity associated protein (FTO), an mRNA N 6 …
been challenging. Fat mass and obesity associated protein (FTO), an mRNA N 6 …
M6AREG: m6A-centered regulation of disease development and drug response
As the most prevalent internal modification in eukaryotic RNAs, N 6-methyladenosine (m6A)
has been discovered to play an essential role in cellular proliferation, metabolic …
has been discovered to play an essential role in cellular proliferation, metabolic …
N6‐methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation
Z Zhang, L Wang, L Zhao, Q Wang… - Clinical and …, 2022 - Wiley Online Library
Background As the most widespread mRNAs modification, N6‐methyladenosine (m6A) is
dynamically and reversibly modulated by methyltransferases and demethylases. ALKBH5 is …
dynamically and reversibly modulated by methyltransferases and demethylases. ALKBH5 is …
[HTML][HTML] Insights into the mechanism underlying crystalline silica-induced pulmonary fibrosis via transcriptome-wide m6A methylation profile
Y Zhang, P Gu, Y Xie, L Fan, X You, S Yang… - Ecotoxicology and …, 2022 - Elsevier
Silicosis is one of the most severe interstitial lung fibrosis diseases worldwide, caused by
crystalline silica exposure. While the mechanisms and pathogenesis underlying silicosis …
crystalline silica exposure. While the mechanisms and pathogenesis underlying silicosis …
Molecular characteristics, oncogenic roles, and relevant immune and pharmacogenomic features of EVA1B in colorectal cancer
B Ma, K Wang, Y Liang, Q Meng, Y Li - Frontiers in Immunology, 2022 - frontiersin.org
Objective EVA1B, a protein coding gene, is a critical paralog of EVA1A gene. Herein, our
study was conducted to investigate the role of EVA1B in colorectal cancer (CRC) …
study was conducted to investigate the role of EVA1B in colorectal cancer (CRC) …
[HTML][HTML] N6-methyladenosine (m6A) in pancreatic cancer: Regulatory mechanisms and future direction
J Li, F Wang, Y Liu, H Wang, B Ni - International Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract N 6-methyladenosine (m 6 A), the most abundant RNA modification in eukaryotes,
plays a pivotal role in regulating many cellular and biological processes. Aberrant m 6 A …
plays a pivotal role in regulating many cellular and biological processes. Aberrant m 6 A …