Harmful free radicals in aging: A narrative review of their detrimental effects on health

YF Mustafa - Indian Journal of Clinical Biochemistry, 2024 - Springer
The production of harmful free radicals (H-FRs), especially those with oxygen or nitrogen
atoms, depends on both internal and environmental causes. The negative effects of H-FRs …

Inflammaging: implications in sarcopenia

E Antuña, C Cachán-Vega, JC Bermejo-Millo… - International Journal of …, 2022 - mdpi.com
In a world in which life expectancy is increasing, understanding and promoting healthy
aging becomes a contemporary demand. In the elderly, a sterile, chronic and low-grade …

Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases

S Ji, M Xiong, H Chen, Y Liu, L Zhou, Y Hong… - … and Targeted Therapy, 2023 - nature.com
The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

Mediation role of recreational physical activity in the relationship between the dietary intake of live microbes and the systemic immune-inflammation index: A real …

Y You, Y Chen, M Wei, M Tang, Y Lu, Q Zhang, Q Cao - Nutrients, 2024 - mdpi.com
The main topic of this research is the relationship between dietary intake of live microbe-
containing (LMC) foods, recreational physical activity (RPA), and the systemic immune …

Fiber-type shifting in sarcopenia of old age: proteomic profiling of the contractile apparatus of skeletal muscles

P Dowling, S Gargan, D Swandulla… - International Journal of …, 2023 - mdpi.com
The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

The dietary inflammatory index and its association with the prevalence of hypertension: A cross-sectional study

N Zhou, ZP Xie, Q Liu, Y Xu, SC Dai, J Lu… - Frontiers in …, 2023 - frontiersin.org
Aims We aim to investigate the association of the Dietary Inflammatory Index (DII) with the
prevalence of hypertension in a large multiracial population in the United States. Methods …

Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism

G Scarfò, S Daniele, E Chelucci, A Rizza, J Fusi… - Scientific Reports, 2023 - nature.com
Aging is the basis for several unfavorable conditions, including cardiovascular diseases
(CVDs). In this sense, regular physical activity (regular PA) has been proven to delay cellular …

Focus on senescence: Clinical significance and practical applications

V Boccardi, ME Orr, MC Polidori… - Journal of Internal …, 2024 - Wiley Online Library
The older population is increasing worldwide, and life expectancy is continuously rising,
predominantly thanks to medical and technological progress. Healthspan refers to the …

Oxidative stress linking obesity and cancer: is obesity a 'Radical trigger'to Cancer?

M Jovanović, S Kovačević, J Brkljačić… - International Journal of …, 2023 - mdpi.com
Obesity is on the rise worldwide, and consequently, obesity-related non-communicable
diseases are as well. Nutritional overload induces metabolic adaptations in an attempt to …

Effects of exercise and physical activity on gut microbiota composition and function in older adults: a systematic review

V Aya, P Jimenez, E Muñoz, JD Ramírez - BMC geriatrics, 2023 - Springer
Background The characterization and research around the gut microbiome in older people
emphasize microbial populations change considerably by losing the diversity of species …