[HTML][HTML] SARS-CoV-2 spike P681R mutation enhances and accelerates viral fusion

A Saito, H Nasser, K Uriu, Y Kosugi, T Irie, K Shirakawa… - 2021 - europepmc.org
During the current SARS-CoV-2 pandemic, a variety of mutations have been accumulated in
the viral genome, and at least five variants of concerns (VOCs) have been considered as the …

SARS-CoV-2 spike P681R mutation, a hallmark of the Delta variant, enhances viral fusogenicity and pathogenicity

A Saito, T Irie, R Suzuki, T Maemura, H Nasser, K Uriu… - BioRxiv, 2021 - biorxiv.org
During the current SARS-CoV-2 pandemic, a variety of mutations have been accumulated in
the viral genome, and at least five variants of concerns (VOCs) have been considered as the …

[HTML][HTML] Pre-existing SARS-CoV-2 immunity influences potency, breadth, and durability of the humoral response to SARS-CoV-2 vaccination

G Mantus, LE Nyhoff, VV Edara, VI Zarnitsyna… - Cell Reports …, 2022 - cell.com
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
highlights the importance of determining the breadth and durability of humoral immunity to …

[HTML][HTML] SARS-CoV-2 Delta variant pathogenesis and host response in Syrian hamsters

S Mohandas, PD Yadav, A Shete, D Nyayanit… - Viruses, 2021 - mdpi.com
B. 1.617 is becoming a dominant Severe Acute Respiratory Syndrome-Coronavirus-2
(SARS-CoV-2) lineage worldwide with many sublineages, of which B. 1.617. 2 is designated …

[HTML][HTML] Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein

MA Tortorici, AC Walls, A Joshi, YJ Park, RT Eguia… - Cell, 2022 - cell.com
Summary The isolation of CCoV-HuPn-2018 from a child respiratory swab indicates that
more coronaviruses are spilling over to humans than previously appreciated. We …

[HTML][HTML] Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade

JC Yam-Puc, Z Hosseini, EC Horner, PP Gerber… - Nature …, 2023 - nature.com
Age-associated B cells (ABC) accumulate with age and in individuals with different
immunological disorders, including cancer patients treated with immune checkpoint …

Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough …

MI Azeem, AK Nooka, U Shanmugasundaram… - Blood cancer …, 2023 - AACR
Patients with multiple myeloma (MM) mount suboptimal neutralizing antibodies (nAb)
following 2 doses of SARS-CoV-2 mRNA vaccines. Currently, circulating SARS-CoV-2 …

[HTML][HTML] The variation of SARS-CoV-2 and advanced research on current vaccines

Y Jiang, Q Wu, P Song, C You - Frontiers in Medicine, 2022 - frontiersin.org
Over the past 2 years, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
caused the coronavirus disease 2019 (COVID-19) and rapidly spread worldwide. In the …

[HTML][HTML] COVID-19: epidemiology and mutations: An update

CJ Hemmer, M Löbermann, EC Reisinger - Der Radiologe, 2021 - Springer
Mutationen von SARS-CoV‑2 können die Ausbreitungsfähigkeit und Infektiosität erhöhen
sowie die Schutzwirkung von Antikörpern vermindern, die nach einer Infektion, einer …

[HTML][HTML] The intestinal microbiota and improving the efficacy of COVID-19 vaccinations

J Chen, L Vitetta, JD Henson, S Hall - Journal of Functional Foods, 2021 - Elsevier
Most COVID-19 cases are mild or asymptomatic and recover well, suggesting that effective
immune responses ensue, which successfully eliminate SARS-CoV-2 viruses. However, a …