Dendritic cells (DCs) comprise heterogeneous subsets, functionally classified into
conventional DCs (cDCs) and plasmacytoid DCs (pDCs). DCs are considered to be …

Coordination of immune responses in the gut is a complex task. In order to fight pathogens
and maintain a defined population of commensal microbes, the mucosal immune system …

Abstract Galectin‐9 (Gal‐9) plays pivotal roles in the modulation of innate and adaptive
immunity to suppress T‐cell‐mediated autoimmune models. However, it remains unclear if …

The capacity of the immune system to distinguish foreign from self-antigen, and to
subsequently eliminate the threat of disease without injuring the host is crucial for survival. It …

Indirect acute lung injury (ALI, not caused by a direct insult to the lung) represents the first
organ dysfunction in trauma patients, with nonpulmonary sepsis being the most common …

We investigated the contribution of lipopolysaccharide (LPS) to adjuvant properties of native
outer membrane vesicles (NOMV), a vaccine candidate for meningococcal B disease …

PURPOSE: Our previous report indicated that carbon ion beam irradiation upregulated
membrane-associated immunogenic molecules, underlining the potential clinical application …

Dendritic cells (DCs) are professional antigen-presenting cells capable of initiating
primary/adaptive immune responses and tolerance. DC functions are regulated by their state …

BACKGROUND: Dendritic cells (DCs) are crucial for the induction of immunity and
tolerance. Despite an improved understanding of the DC-mediated control of TH1-biased …

Sepsis is defined as severe systemic inflammation in response to invading pathogens, or an
uncontrolled hyperinflammatory response, as mediated by the release of various …