[HTML][HTML] miRNAs in pancreatic cancer progression and metastasis

ETY Mok, JL Chitty, TR Cox - Clinical & Experimental Metastasis, 2024 - Springer
Small non-coding RNA or microRNA (miRNA) are critical regulators of eukaryotic cells.
Dysregulation of miRNA expression and function has been linked to a variety of diseases …

[HTML][HTML] miR-18a and miR-106a signatures in plasma small EVs are promising biomarkers for early detection of pancreatic ductal adenocarcinoma

X Xu, K Bhandari, C Xu, K Morris, WQ Ding - International Journal of …, 2023 - mdpi.com
Pancreatic cancer is the third leading cause of cancer-related death in the United States.
Pancreatic ductal adenocarcinoma (PDAC) is the major form of pancreatic cancer with the …

[HTML][HTML] Emerging Horizons in the Diagnosis of Pancreatic Cancer: The Role of Circulating microRNAs as Early Detection Biomarkers for Pancreatic Ductal …

I Reyaz, B Khan, N James, H Azhar, A Rehman… - Cureus, 2024 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a poor
prognosis, primarily due to a late diagnosis. Recent studies have focused on identifying non …

[HTML][HTML] The Multifaceted Role of miR-21 in Pancreatic Cancers

C Chen, L Demirkhanyan, CS Gondi - Cells, 2024 - mdpi.com
With the lack of specific signs and symptoms, pancreatic ductal adenocarcinoma (PDAC) is
often diagnosed at late metastatic stages, resulting in poor survival outcomes. Among …

[HTML][HTML] Expression of Selected miRNAs in Normal and Cancer-Associated Fibroblasts and in BxPc3 and MIA PaCa-2 Cell Lines of Pancreatic Ductal …

V Mandys, A Popov, R Gürlich, J Havránek… - International Journal of …, 2023 - mdpi.com
Therapy for pancreatic ductal adenocarcinoma remains challenging, and the chances of a
complete cure are very limited. As in other types of cancer, the expression and role of …

[HTML][HTML] Expression of Selected miRNAs in Undifferentiated Carcinoma with Osteoclast-like Giant Cells (UCOGC) of the Pancreas: Comparison with Poorly …

A Popov, J Hrudka, A Szabó, M Oliverius, Z Šubrt… - Biomedicines, 2024 - mdpi.com
Undifferentiated carcinoma with osteoclast-like giant cells (UCOGC) of the pancreas
represents a rare subtype of pancreatic ductal adenocarcinoma (PDAC). Despite a distinct …

Five plus Three for the Pancreas

JM Löhr, K Pantel - Clinical Cancer Research, 2023 - AACR
Preneoplastic high-risk lesions in the pancreas need to be differentiated from low-risk
lesions warranting surveillance and eventually surgical intervention. Imaging is used so far; …

[HTML][HTML] Increased Levels of miR-15b-5p and miR-20b-5p in Pancreatic Ductal Adenocarcinoma with Hepatic Metastases

M Dobre, RC Poenaru, AM Niculae, C Vladut, V Herlea… - Genes, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal forms of
cancer. The symptoms appear in advanced stages, and diagnostic and prognostic tests for …

[HTML][HTML] Establishment and validation of a prognostic signature for pancreatic ductal adenocarcinoma based on lactate metabolism-related genes

X Huang, C Zhao, Y Han, S Li - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and
lethal malignancy with poor prognosis. To improve patient outcomes, it is necessary to gain …

Master Regulators of Causal Networks in Intestinal-and Diffuse-Type Gastric Cancer and the Relation to RNA Virus Infection Pathway

S Tanabe, S Quader, H Cabral, EJ Perkins, H Yokozaki… - 2024 - preprints.org
The causal networks are important for understanding the signaling alterations in diseases.
To reveal the network pathways affected in epithelial-mesenchymal transition (EMT) and …