It has been argued that reduced inbreeding depression and associated increased heterosis
(hybrid vigor), due to greater gene flow between human subpopulations, is the cause of the …

Dominance is a fundamental parameter in genetics, determining the dynamics of natural
selection on deleterious and beneficial mutations, the patterns of genetic variation in natural …

Using data from the Midlife Development in the USA (MIDUS) sample (3070 men and 3182
women) and the Wisconsin Longitudinal Study (WLS; 2240 men and 2346 women), we …

The children of related parents show increased risk of early mortality. The Native American
genome typically exhibits long stretches of homozygosity, and Latin Americans are highly …

Background Children of consanguineous parents have a higher risk of infant and childhood
mortality, morbidity and intellectual and developmental disability. Methods Using a …

This book was initially written and compiled before the 2020 US presidential election. Since
that time, much has occurred. This preface both acknowledges the rapidly changing events …

Aim Inbreeding is thought to affect the morphometric parameters leading to lower health
status among the progeny. The present study was aimed to investigate the repercussions of …

The multi-millenia long history between dogs and humans has justly placed them at the
forefront of archeological and genomic research. Despite ongoing efforts including the …

Genome-wide sequencing of human populations has revealed substantial variation among
genes in the intensity of purifying selection acting on damaging genetic variants. While …

Introduction It has been frequently suggested that overall genomic heterozygosity and,
particularly, heterozygosity of loci on the so-called major histocompatibility complex (MHC) …