The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

The diverse and dynamic microbial community of the human gastrointestinal tract plays a
vital role in health, with gut microbiota supporting the development and function of the gut …

Pectins are dietary fibers with different structural characteristics. Specific pectin structures
can influence the gastrointestinal immune barrier by directly interacting with immune cells or …

Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …

The intestine plays an essential role in integrating immunity and nutrient digestion and
absorption. Adjacent intestinal epithelia form tight junctions (TJs) that are essential to the …

Background/Aims: Short-chain fatty acids (SCFAs) are the major energy resources of
intestinal epithelial cells. It has been reported that SCFAs can repair the dysfunction of …

Commensal interactions between the enteric microbiota and distal intestine play important
roles in regulating human health. Short-chain fatty acids (SCFAs), such as butyrate …

The initiation of intestinal inflammation involves complex intercellular cross-talk of
inflammatory cells, including the epithelial and immune cells, and the gut microbiome. This …

In large amounts, alcohol and its metabolites can overwhelm the gastrointestinal tract (GI)
and liver and lead to damage both within the GI and in other organs. Specifically, alcohol …

The mucus layer coating the gastrointestinal tract is the front line of innate host defense,
largely because of the secretory products of intestinal goblet cells. Goblet cells synthesize …