Breast cancer is a major global health problem and major cause of mortality. Although
mortality trends are declining in high-income countries, trends are increasing in low-and …

Objective This article describes a scalable, performant, sustainable global network of
electronic health record data for biomedical and clinical research. Materials and Methods …

As a result of recent advances in cancer research and “precision medicine” approaches, ie
the idea of treating each patient with the right drug at the right time, more and more cancer …

Objective We summarized a decade of new research focusing on semantic data integration
(SDI) since 2009, and we aim to:(1) summarize the state-of-art approaches on integrating …

Purpose Biomedical research is being catalyzed by the vast amount of data rapidly collected
through the application of information technologies (IT). Despite IT advances, the methods …

Background To reduce cancer mortality and improve cancer outcomes, it is critical to
understand the various cancer risk factors (RFs) across different domains (eg, genetic …

Adaptable utilization of clinical data collected from multiple centers, prompted by the need to
overcome the shifts between the dataset distributions, and exploit these different datasets for …

Background There is limited guidance for using common drug therapies in the context of
multimorbidity. In part, this is because their effectiveness for patients with specific …

Processing and managing sensitive health data requires a high standard of security and
privacy measures to ensure that all ethical and legal requirements are respected. Data …

Objective The development of clinical research informatics tools and workflow processes
associated with re-engaging biobank participants has become necessary as genomic …