The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

We review theoretical and numerical models of the glymphatic system, which circulates
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …

Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and
through the brain transports not only those water-like fluids but also any solutes they carry …

Clearance of neurotoxic brain proteins via cerebrospinal fluid (CSF) to blood has recently
emerged to be crucial, and plasma biomarkers of neurodegeneration were newly introduced …

The neurovascular unit (NVU) is a conceptual framework that has been proposed to better
explain the relationships between the neural cells and blood vessels in the human brain …

The ocular glymphatic system supports bidirectional fluid transport along the optic nerve,
thereby removes metabolic wastes including amyloid-β. To better understand this biological …

In the past, water homeostasis of the brain was understood as a certain quantitative
equilibrium of water content between intravascular, interstitial, and intracellular spaces …

Background The modulation of neuroinflammation is a new direction that may alleviate the
early brain injury after subarachnoid hemorrhage (SAH). Brain resident microglia …

The recent discovery of the meningeal lymphatic vessels (mLVs) and glymphatic pathways
has challenged the long-lasting dogma that the central nervous system (CNS) lacks a …

Acute sleep deprivation has been shown to affect cerebrospinal fluid and plasma
concentrations of biomarkers associated with neurodegeneration, though the mechanistic …