[HTML][HTML] COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches

S Kakavandi, B Hajikhani, P Azizi, F Aziziyan… - Cell Communication and …, 2024 - Springer
Extensive research in countries with high sociodemographic indices (SDIs) to date has
shown that coronavirus disease 2019 (COVID-19) may be directly associated with more …

[HTML][HTML] VHH Structural Modelling Approaches: A Critical Review

P Vishwakarma, AM Vattekatte, N Shinada… - International Journal of …, 2022 - mdpi.com
VHH, ie, VH domains of camelid single-chain antibodies, are very promising therapeutic
agents due to their significant physicochemical advantages compared to classical …

[HTML][HTML] Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron

H Ma, X Zhang, P Zheng, PH Dube, W Zeng, S Chen… - Cell Research, 2022 - nature.com
SARS-CoV-2 variants with adaptive mutations have continued to emerge, causing fresh
waves of infection even amongst vaccinated population. The development of broad …

Applications of nanobodies in the prevention, detection, and treatment of the evolving SARS-CoV-2

W Wang, Y Hu, B Li, H Wang, J Shen - Biochemical Pharmacology, 2023 - Elsevier
Global health and economy are deeply influenced by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and its newly emerging variants. Nanobodies with nanometer …

[HTML][HTML] Nanobodies: cOVID-19 and future perspectives

G Valenzuela-Nieto, Z Miranda-Chacon… - Frontiers in Drug …, 2022 - frontiersin.org
The COVID-19 pandemic has driven biotechnological developments to provide new and
more effective tools for prophylaxis, diagnosis, and therapy. Historically, monoclonal …

A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern

D Wu, J Cong, J Wei, J Hu, W Sun, W Ran… - International Journal …, 2023 - Taylor & Francis
Background The emergence of the coronavirus disease 2019 (COVID-19) pandemic and the
new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern …

[HTML][HTML] Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins

C Yu, W Ding, L Zhu, Y Zhou, Y Dong, L Li, J Liu… - Iscience, 2023 - cell.com
Influenza A virus poses a constant challenge to human health. The highly conserved
influenza matrix-2 (M2) protein is an attractive target for the development of a universal …

[HTML][HTML] Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants

MF Pavan, M Bok, RB San Juan, JP Malito… - bioRxiv, 2023 - ncbi.nlm.nih.gov
In this work, we developed llama-derived nanobodies (Nbs) directed to the receptor binding
domain (RBD) and other domains of the Spike (S) protein of SARS-CoV-2. Nanobodies …

Current and emerging pharmacological treatments for respiratory syncytial virus infection in high-risk infants

JA Soto, RA Loaiza, S Echeverría… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The human respiratory syncytial virus (hRSV) is the leading cause of respiratory
infections in children, older adults, and patients with comorbidities. Since the hRSV …

[HTML][HTML] Therapeutic antibodies and alternative formats against SARS-CoV-2

RR Winiger, L Perez - Antiviral Research, 2024 - Elsevier
The COVID-19 pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) heavily burdened the entire world. Despite a prompt generation of vaccines …