Iron metabolism and immune regulation

S Ni, Y Yuan, Y Kuang, X Li - Frontiers in immunology, 2022 - frontiersin.org
Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly
controlled in the body, disturbance of iron homeostasis under certain type of condition leads …

Lipid peroxidation and iron metabolism: two corner stones in the homeostasis control of ferroptosis

L Rochette, G Dogon, E Rigal, M Zeller… - International journal of …, 2022 - mdpi.com
Regulated cell death (RCD) has a significant impact on development, tissue homeostasis,
and the occurrence of various diseases. Among different forms of RCD, ferroptosis is …

GDF15, an emerging key player in human aging

M Conte, C Giuliani, A Chiariello, V Iannuzzi… - Ageing research …, 2022 - Elsevier
Abstract Growth differentiation factor 15 (GDF15) is recently emerging not only as a stress-
related mitokine, but also as a key player in the aging process, being one of the most up …

The potential role of growth differentiation factor 15 in COVID-19: a corollary subjective effect or not?

AO Babalghith, HM Al-Kuraishy, AI Al-Gareeb… - Diagnostics, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is primarily caused by various forms of severe acute
respiratory syndrome coronavirus type 2 (SARS-CoV-2) variants. COVID-19 is characterized …

Coping with stress: the mitokine GDF-15 as a biomarker of COVID-19 severity

DS Ahmed, S Isnard, C Berini, J Lin, JP Routy… - Frontiers in …, 2022 - frontiersin.org
Growth differentiation factor 15 (GDF-15) is a transforming growth factor (TGF)-β superfamily
cytokine that plays a central role in metabolism regulation. Produced in response to …

GDF15 as a key disease target and biomarker: Linking chronic lung diseases and ageing

Y Wan, J Fu - Molecular and cellular biochemistry, 2024 - Springer
Abstract Growth differentiation factor 15 (GDF15), a member of the transforming growth
factor-beta superfamily, is expressed in several human organs. In particular, it is highly …

Kaempferol has potential anti‐coronavirus disease 2019 (COVID‐19) targets based on bioinformatics analyses and pharmacological effects on endotoxin‐induced …

Y Sun, Q Tao, Y Cao, T Yang, L Zhang… - Phytotherapy …, 2023 - Wiley Online Library
COVID‐19 has infected 272 million patients and caused 5.33 million deaths around the
world, and it remains the main global threat. Previous studies revealed that Chinese …

Growth differentiation factor-15 in immunity and aging

BD Pence - Frontiers in Aging, 2022 - frontiersin.org
Aging increases susceptibility to and severity of a variety of chronic and infectious diseases.
Underlying this is dysfunction of the immune system, including chronic increases in low …

Emerging roles of growth differentiation factor 15 in immunoregulation and pathogenesis

J Reyes, GS Yap - The Journal of Immunology, 2023 - journals.aai.org
Abstract Growth differentiation factor 15 (GDF-15) is a cytokine that is widely used as a
biomarker for the severity of diverse disease states. It also has been shown to play a …

An improved Fuzzy based GWO algorithm for predicting the potential host receptor of COVID-19 infection

A Achom, R Das, P Pakray - Computers in Biology and Medicine, 2022 - Elsevier
Abstract Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) and has infected millions worldwide. SARS-CoV-2 spike …