TH Evering, KW Chew, MJ Giganti, C Moser… - Annals of internal …, 2023 - acpjournals.org
Background: Development of safe and effective SARS-CoV-2 therapeutics is a high priority. Amubarvimab and romlusevimab are noncompeting anti–SARS-CoV-2 monoclonal …
Y Yang, F Li, L Du - Journal of Nanobiotechnology, 2024 - Springer
Nanobodies, single-domain antibodies derived from variable domain of camelid or shark heavy-chain antibodies, have unique properties with small size, strong binding affinity, easy …
L Abassi, F Bertoglio, Ž Mačak Šafranko, T Schirrmann… - Viruses, 2023 - mdpi.com
As of now, the COVID-19 pandemic has spread to over 770 million confirmed cases and caused approximately 7 million deaths. While several vaccines and monoclonal antibodies …
S Iketani, DD Ho - Cell Chemical Biology, 2024 - cell.com
Over four years have passed since the beginning of the COVID-19 pandemic. The scientific response has been rapid and effective, with many therapeutic monoclonal antibodies and …
A Chiyyeadu, G Asgedom, M Bruhn, C Rocha… - Clinical …, 2024 - Elsevier
The devastating impact of COVID-19 on global health shows the need to increase our pandemic preparedness. Recombinant therapeutic antibodies were successfully used to …
MC Choudhary, R Deo, TH Evering… - The Journal of …, 2024 - academic.oup.com
Background Monoclonal antibodies (mAbs) represent a crucial antiviral strategy for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but it is unclear whether …
Y Xu, Y Liu, R Zheng, S Si, Y Xi, X Deng, G Wang… - Intensive care …, 2023 - Springer
Objective Early intervention with neutralizing antibodies is considered to be effective in preventing disease progression in patients with mild to moderate COVID-19 infection …
SARS-CoV-2 enters cells via binding of the surface-exposed spike protein RBD to host cell ACE2 receptors. Therefore, in this study, we designed a scFv (single-chain fragment …
J Zhao, J Zhu, C Huang, X Zhu, Z Zhu, Q Wu… - Frontiers in …, 2022 - frontiersin.org
Background Since the global epidemic of the coronavirus disease 2019 (COVID-19), a large number of immunological studies related to COVID-19 have been published in various …