Personalized medicine tailors therapies, disease prevention, and health maintenance to the
individual, with pharmacogenomics serving as a key tool to improve outcomes and prevent …

Human genetics research has discovered thousands of proteins associated with complex
and rare diseases. Genome-wide association studies (GWAS) and studies of Mendelian …

This paper explores the transformative role of pharmacists in integrating pharmacogenomics
into clinical practice. Pharmacogenomics, the study of genetic influences on drug response …

Adverse drug reactions (ADRs) rank as one of the top 10 leading causes of death and
illness in developed countries. ADRs show differential features depending upon genotype …

Pharmacogenomics (PGx) is a key subset of precision medicine that relates genomic
variation to individual response to pharmacotherapy. We assessed longitudinal trends in US …

Personalized treatment of complex diseases relies on combined medication. However, the
occurrence of unexpected drug–drug interactions (DDIs) in these combinations can lead to …

Background Cohort and cost‐effectiveness studies suggest that measuring variation in
genes that influence metabolism of common drugs could improve antidepressant treatment …

Pharmacogenomics is a study of how the genome background is associated with drug
resistance and how therapy strategy can be modified for a certain person to achieve benefit …

Introduction Cholinergic dysfunction, demonstrated in the late 1970s and early 1980s, led to
the introduction of acetylcholinesterase inhibitors (AChEIs) in 1993 (Tacrine) to enhance …

Symptomatic interventions for patients with dementia involve anti-dementia drugs to improve
cognition, psychotropic drugs for the treatment of behavioral disorders (BDs), and different …