Remdesivir in COVID-19: A critical review of pharmacology, pre-clinical and clinical studies

AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2020 - Elsevier
Background & aims Remdesivir is a broad spectrum anti-viral drug that has shown to inhibit
SARS-CoV-2, in vitro and in vivo. In absence of any effective treatment for SARS-CoV-2 …

Supportive treatment with tocilizumab for COVID-19: a systematic review

SK Alzghari, VS Acuna - Journal of Clinical Virology, 2020 - Elsevier
2. Methods A systematic review was performed according to the Preferred Reporting Items
for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A literature search was …

Observational study of hydroxychloroquine in hospitalized patients with Covid-19

J Geleris, Y Sun, J Platt, J Zucker… - … England Journal of …, 2020 - Mass Medical Soc
Background Hydroxychloroquine has been widely administered to patients with Covid-19
without robust evidence supporting its use. Methods We examined the association between …

[HTML][HTML] Challenges in the management of SARS-CoV2 infection: the role of oral bacteriotherapy as complementary therapeutic strategy to avoid the progression of …

G d'Ettorre, G Ceccarelli, M Marazzato… - Frontiers in …, 2020 - frontiersin.org
Background: Gastrointestinal disorders are frequent in COVID-19 and SARS-CoV-2 has
been hypothesized to impact on host microbial flora and gut inflammation, infecting intestinal …

[HTML][HTML] Tocilizumab for treatment of severe COVID-19 patients: preliminary results from SMAtteo COvid19 REgistry (SMACORE)

M Colaneri, L Bogliolo, P Valsecchi, P Sacchi… - Microorganisms, 2020 - mdpi.com
Objective: This study aimed to assess the role of Tocilizumab therapy (TCZ) in terms of ICU
admission and mortality rate of critically ill patients with severe COVID-19 pneumonia …

[HTML][HTML] Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated international task force …

C Bai, SH Chotirmall, J Rello, GA Alba… - European …, 2020 - Eur Respiratory Soc
Background Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute
respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby …

Asthma and COVID‐19 in children: a systematic review and call for data

JA Castro‐Rodriguez, E Forno - Pediatric pulmonology, 2020 - Wiley Online Library
Rationale Whether asthma constitutes a risk factor for coronavirus disease‐2019 (COVID‐
19) is unclear. Here, we aimed to assess whether asthma, the most common chronic …

[HTML][HTML] Impact of renal function on admission in COVID-19 patients: an analysis of the international HOPE COVID-19 (Health Outcome Predictive Evaluation for …

A Uribarri, IJ Nunez-Gil, A Aparisi… - Journal of …, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is a disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite its international …

[HTML][HTML] Role of Lopinavir/Ritonavir in the treatment of Covid-19: a review of current evidence, guideline recommendations, and perspectives

S Meini, A Pagotto, B Longo, I Vendramin… - Journal of clinical …, 2020 - mdpi.com
A life-threatening respiratory illness (COVID-19) due to severe acute respiratory syndrome
(SARS)-CoV-2 coronavirus was first described in December 2019 in Wuhan (China), rapidly …

Tratamiento farmacológico de la COVID-19: revisión narrativa de los Grupos de Trabajo de Enfermedades Infecciosas y Sepsis (GTEIS) y del Grupo de Trabajo de …

E Díaz, RA Menéndez, PV Cortés, MG Escapa… - Medicina intensiva, 2021 - Elsevier
La infección por el virus SARS-CoV-2, denominada COVID-19 (COronaVIrus Disease 19),
fue detectada inicialmente en China en diciembre 2019, y posteriormente se ha diseminado …