[HTML][HTML] Immunomodulatory mechanisms and therapeutic potential of mesenchymal stem cells

G Yang, X Fan, Y Liu, P Jie, M Mazhar, Y Liu… - Stem Cell Reviews and …, 2023 - Springer
Mesenchymal stem cells (MSCs) are regarded as highly promising cells for allogeneic cell
therapy, owing to their multipotent nature and ability to display potent and varied functions in …

[HTML][HTML] Function and mechanism of mesenchymal stem cells in the healing of diabetic foot wounds

X Yu, P Liu, Z Li, Z Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetes has become a global public health problem. Diabetic foot is one of the most severe
complications of diabetes, which often places a heavy economic burden on patients and …

[HTML][HTML] Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK …

Y Li, J Huang, J Wang, S Xia, H Ran, L Gao… - Journal of …, 2023 - Springer
Background Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) engraftment
is a promising therapy for acute ischemic stroke (AIS). However, the harsh ischemic …

[HTML][HTML] Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse model

Y Shi, X Yang, S Wang, Y Wu, L Zheng, Y Tang… - Stem cell research & …, 2022 - Springer
Background and aims Human umbilical cord mesenchymal stem cells (hUC-MSCs) are
increasingly being studied in clinical trials of end-stage liver disease because of their good …

Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)

N Prakash, J Kim, J Jeon, S Kim, Y Arai… - Biomaterials …, 2023 - spj.science.org
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …

[HTML][HTML] Exosomes derived from umbilical cord mesenchymal stem cells treat cutaneous nerve damage and promote wound healing

Z Zhu, X Zhang, H Hao, H Xu, J Shu, Q Hou… - Frontiers in cellular …, 2022 - frontiersin.org
Wound repair is a key step in the treatment of skin injury caused by burn, surgery, and
trauma. Various stem cells have been proven to promote wound healing and skin …

[HTML][HTML] Clinical trials targeting secondary damage after traumatic spinal cord injury

ZZ Khaing, JY Chen, G Safarians, S Ezubeik… - International journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) often causes loss of sensory and motor function resulting in a
significant reduction in quality of life for patients. Currently, no therapies are available that …

[HTML][HTML] Comparison of therapeutic effects of mesenchymal stem cells from umbilical cord and bone marrow in the treatment of type 1 diabetes

W Zhang, Q Ling, B Wang, K Wang, J Pang… - Stem cell research & …, 2022 - Springer
Background The therapeutic potential of mesenchymal stem cells (MSCs) in type 1 diabetes
(T1D) has been demonstrated in both preclinical and clinical studies. MSCs that have been …

[HTML][HTML] Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via …

K Li, G Yan, H Huang, M Zheng, K Ma, X Cui… - Journal of …, 2022 - Springer
Osteoarthritis (OA) is a degenerative illness that greatly impacts the life quality of patients.
Currently, the therapeutic approaches for OA are very limited in clinical. The extracellular …

[HTML][HTML] Mesenchymal stem cells in the pathogenesis and therapy of autoimmune and autoinflammatory diseases

LN Zaripova, A Midgley, SE Christmas… - International Journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) modulate immune responses and maintain self-tolerance.
Their trophic activities and regenerative properties make them potential …