[HTML][HTML] Alleviating anxiety and taming trauma: novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder

N Singewald, SB Sartori, A Reif, A Holmes - Neuropharmacology, 2023 - Elsevier
Psychiatric disorders associated with psychological trauma, stress and anxiety are a highly
prevalent and increasing cause of morbidity worldwide. Current therapeutic approaches …

The emerging role of the gut microbiome in posttraumatic stress disorder

S Ke, J Hartmann, KJ Ressler, YY Liu… - Brain, behavior, and …, 2023 - Elsevier
Posttraumatic stress disorder (PTSD) occurs in some people following exposure to a
terrifying or catastrophic event involving actual/threatened death, serious injury, or sexual …

Reducing intrusive memories after trauma via an imagery-competing task intervention in COVID-19 intensive care staff: a randomised controlled trial

L Iyadurai, J Highfield, M Kanstrup, A Markham… - Translational …, 2023 - nature.com
Intrusive memories (IMs) after traumatic events can be distressing and disrupt mental health
and functioning. We evaluated the impact of a brief remotely-delivered digital imagery …

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

CM Nievergelt, AX Maihofer, EG Atkinson, CY Chen… - Nature Genetics, 2024 - nature.com
Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability
than most other psychiatric disorders. The contribution to biological understanding from …

Thalamic nucleus reuniens coordinates prefrontal-hippocampal synchrony to suppress extinguished fear

MS Totty, T Tuna, KR Ramanathan, J Jin… - Nature …, 2023 - nature.com
Traumatic events result in vivid and enduring fear memories. Suppressing the retrieval of
these memories is central to behavioral therapies for pathological fear. The medial prefrontal …

Reversal of hyperactive higher-order thalamus attenuates defensiveness in a mouse model of PTSD

K Xi, H Xiao, X Huang, Z Yuan, M Liu, H Mao, H Liu… - Science …, 2023 - science.org
Posttraumatic stress disorder (PTSD) is a highly prevalent and debilitating psychiatric
disease often accompanied by severe defensive behaviors, preventing individuals from …

The psychiatric dysfunctions associated to the labor estrés in professionals of the education

MNV Montano - Interdisciplinary Rehabilitation/Rehabilitacion …, 2023 - ri.saludcyt.ar
Stress caused by working conditions or environments continues to be a scourge that affects
workers worldwide and can affect physical and mental health, even favoring the emergence …

Psychiatric sequelae of traumatic brain injury—future directions in research

LM Li, A Carson, K Dams-O'Connor - Nature Reviews Neurology, 2023 - nature.com
Despite growing appreciation that traumatic brain injury (TBI) is an important public health
burden, our understanding of the psychiatric and behavioural consequences of TBI remains …

Lifetime posttraumatic stress disorder as a predictor of mortality: a systematic review and meta-analysis

D Nilaweera, AZZ Phyo, AB Teshale, HL Htun… - BMC psychiatry, 2023 - Springer
Abstract Background Posttraumatic Stress Disorder (PTSD) could potentially increase the
risk of mortality, and there is a need for a meta-analysis to quantify this association. This …

360-degree perspectives on obesity

M Cuciureanu, CC Caratașu, L Gabrielian… - Medicina, 2023 - mdpi.com
Alarming statistics show that the number of people affected by excessive weight has
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …