Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …

To discover new molecules or review the biological activity and toxicity of therapeutic
substances, drug development, and research relies on robust biological systems to obtain …

Convergent evidence associates exposure to endocrine disrupting chemicals (EDCs) with
major human diseases, even at regulation-compliant concentrations. This might be because …

Abstract N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPD-quinone)
is a degradation product of 6PPD, an antioxidant widely used in rubber tires. 6PPD-quinone …

Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …

With the continuous development of precise detection technology, more and more pollutants
have been detected in the environment. Among them, neurotoxic pollutants have attracted …

The Wolfram syndrome is a rare autosomal recessive disease affecting many organs with
life-threatening consequences; currently, no treatment is available. The disease is caused …

The effects of polystyrene microplastic (PS-MP) size on neurotoxicity remain to be evaluated
at various microsizes, and the seizurogenic effects of PS-MPs are unknown. This study …

Perfluoroalkyl substances (PFAS) are a class of synthetic chemicals that are persistent in the
environment. Due to adverse health outcomes associated with longer chain PFAS, shorter …

The literature has largely shown the toxicity of petroleum-based PLA biomicroplastics
(PLABioMPs) and encouraged the production of alternative materials to replace their use …