Events in fetal life impact long-term health outcomes. The placenta is the first organ to form
and is the site of juxtaposition between the maternal and fetal circulations. Most diseases of …

In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …

Labor resembles an inflammatory response that includes secretion of cytokines/chemokines
by resident and infiltrating immune cells into reproductive tissues and the maternal/fetal …

The concept that pregnancy is associated with immune suppression has created a myth of
pregnancy as a state of immunological weakness and, therefore, of increased susceptibility …

Citation Mor G, Cardenas I. The immune system in pregnancy: a unique complexity. Am J
Reprod Immunol 2010 Abstract Placental immune response and its tropism for specific …

Inflammation is essential for successful embryo implantation, pregnancy maintenance and
delivery. In the last decade, important advances have been made in regard to endogenous …

Background—Preterm birth leads to an early switch from fetal to postnatal circulation before
completion of left ventricular in utero development. In animal studies, this results in an …

Inflammation is a process by which tissues respond to various insults. It is characterized by
upregulation of chemokines, cytokines, and pattern recognition receptors that sense …