[PDF][PDF] A systematic review of multimodal brain age studies: Uncovering a divergence between model accuracy and utility

RJ Jirsaraie, AJ Gorelik, MM Gatavins, DA Engemann… - Patterns, 2023 - cell.com
Brain aging is a complex, multifaceted process that can be challenging to model in ways that
are accurate and clinically useful. One of the most common approaches has been to apply …

[HTML][HTML] Explaining variation in individual aging, its sources, and consequences: A comprehensive conceptual model of human aging

K Rothermund, C Englert, D Gerstorf - Gerontology, 2023 - karger.com
We define aging as a characteristic deterioration in one (or more) observable attributes of an
organism that typically occurs during later life. With this narrow functional definition, we gain …

[HTML][HTML] Quantifying Brain and Cognitive Maintenance as Key Indicators for Sustainable Cognitive Aging: Insights from the UK Biobank

L Lin, M Xiong, Y Jin, W Kang, S Wu, S Sun, Z Fu - Sustainability, 2023 - mdpi.com
Age-related cognitive decline is a global phenomenon that affects individuals worldwide.
The course and extent of this decline are influenced by numerous factors, such as genetics …

[HTML][HTML] Brain health in diverse settings: How age, demographics and cognition shape brain function

H Hernandez, S Baez, V Medel, S Moguilner… - NeuroImage, 2024 - Elsevier
Diversity in brain health is influenced by individual differences in demographics and
cognition. However, most studies on brain health and diseases have typically controlled for …

[HTML][HTML] Feasibility of brain age predictions from clinical T1-weighted MRIs

PA Valdes-Hernandez, CL Nodarse, JH Cole… - Brain Research …, 2023 - Elsevier
An individual's brain predicted age minus chronological age (brain-PAD) obtained from
MRIs could become a biomarker of disease in research studies. However, brain age reports …

[HTML][HTML] Toward MR protocol-agnostic, unbiased brain age predicted from clinical-grade MRIs

PA Valdes-Hernandez, C Laffitte Nodarse… - Scientific Reports, 2023 - nature.com
The difference between the estimated brain age and the chronological age ('brain-PAD')
could become a clinical biomarker. However, most brain age models were developed for …

Brain Age Estimation with a Greedy Dual-Stream Model for Limited Datasets

I Kianian, H Sajedi - Neurocomputing, 2024 - Elsevier
Brain age estimation involves predicting an individual's biological age from their brain
images. This process offers valuable insights into the aging process and the progression of …

Age Prediction Using Resting-State Functional MRI

JR Chang, ZF Yao, S Hsieh, TEM Nordling - Neuroinformatics, 2024 - Springer
The increasing lifespan and large individual differences in cognitive capability highlight the
importance of comprehending the aging process of the brain. Contrary to visible signs of …

Genome-wide analysis of brain age identifies 25 associated loci and unveils relationships with mental and physical health

P Jawinski, H Forstbach, H Kirsten, F Beyer, A Villringer… - medRxiv, 2023 - medrxiv.org
Neuroimaging and machine learning are opening up new opportunities in studying
biological aging mechanisms. In this field,'brain age gap'has emerged as promising MRI …

Diffusion deep learning for brain age prediction and longitudinal tracking in children through adulthood

A Zapaishchykova, D Tak, Z Ye, KX Liu… - Imaging …, 2024 - direct.mit.edu
Deep learning (DL)-based prediction of biological age in the developing human from a brain
magnetic resonance imaging (MRI)(“brain age”) may have important diagnostic and …