Over the past 500 years, North America has been the site of ongoing mixing of Native
Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave …

Population mixture is an important process in biology. We present a suite of methods for
learning about population mixtures, implemented in a software package called …

Given the importance of Africa to studies of human origins and disease susceptibility,
detailed characterization of African genetic diversity is needed. The African Genome …

As the data resulting from modern genotyping tools are astoundingly complex, genotyping
studies require great care in the sampling design, genotyping, data analysis and …

Modern genetic data combined with appropriate statistical methods have the potential to
contribute substantially to our understanding of human history. We have developed an …

Genotype imputation is a statistical technique that is often used to increase the power and
resolution of genetic association studies. Imputation methods work by using haplotype …

Genetic admixture of divergent intraspecific lineages is increasingly suspected to have an
important role in the success of colonising populations. However, admixture is not a …

Through their domestication and subsequent selection, sheep have been adapted to thrive
in a diverse range of environments. To characterise the genetic consequence of both …

The advent of genome-wide dense variation data provides an opportunity to investigate
ancestry in unprecedented detail, but presents new statistical challenges. We propose a …

Searching for genetic variants with unusual differentiation between subpopulations is an
established approach for identifying signals of natural selection. However, existing methods …