Host–pathogen coevolution in human tuberculosis

S Gagneux - … Transactions of the Royal Society B …, 2012 - royalsocietypublishing.org
Tuberculosis (TB) is a disease of antiquity. Yet TB today still causes more adult deaths than
any other single infectious disease. Recent studies show that contrary to the common view …

[图书][B] Anthropology of modern human teeth

GR Scott, CG Turner - 1997 - cambridge.org
All humans share certain components of tooth structure, but show variation in size and
morphology around this shared pattern. This book presents a worldwide synthesis of the …

Ancient West African foragers in the context of African population history

M Lipson, I Ribot, S Mallick, N Rohland, I Olalde… - Nature, 2020 - nature.com
Our knowledge of ancient human population structure in sub-Saharan Africa, particularly
prior to the advent of food production, remains limited. Here we report genome-wide DNA …

Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations

FSG Kehdy, MH Gouveia, M Machado… - Proceedings of the …, 2015 - National Acad Sciences
While South Americans are underrepresented in human genomic diversity studies, Brazil
has been a classical model for population genetics studies on admixture. We present the …

Genome-wide association studies in diverse populations

NA Rosenberg, L Huang, EM Jewett… - Nature Reviews …, 2010 - nature.com
Genome-wide association (GWA) studies have identified a large number of SNPs
associated with disease phenotypes. As most GWA studies have been performed in …

[PDF][PDF] Uganda genome resource enables insights into population history and genomic discovery in Africa

D Gurdasani, T Carstensen, S Fatumo, G Chen… - Cell, 2019 - cell.com
Genomic studies in African populations provide unique opportunities to understand disease
etiology, human diversity, and population history. In the largest study of its kind, comprising …

[HTML][HTML] An examination of polygenic score risk prediction in individuals with first-episode psychosis

E Vassos, M Di Forti, J Coleman, C Iyegbe, D Prata… - Biological …, 2017 - Elsevier
Abstract Background Polygenic risk scores (PRSs) have successfully summarized genome-
wide effects of genetic variants in schizophrenia with significant predictive power. In a …

Mycobacterium tuberculosis: ecology and evolution of a human bacterium

AL Banuls, A Sanou, NT Van Anh… - Journal of medical …, 2015 - microbiologyresearch.org
Some species of the Mycobacterium tuberculosis complex (MTBC), particularly
Mycobacterium tuberculosis, which causes human tuberculosis (TB), are the first cause of …

Promoting the genomic revolution in Africa through the Nigerian 100K Genome Project

S Fatumo, A Yakubu, O Oyedele, J Popoola… - Nature Genetics, 2022 - nature.com
To leverage the genetic diversity in Nigeria, we established the Non-Communicable
Diseases Genetic Heritage Study (NCD-GHS) consortium to help produce a comprehensive …

Steroidogenesis: unanswered questions

WL Miller - Trends in Endocrinology & Metabolism, 2017 - cell.com
Until the mid-1980s studies of steroidogenesis largely depended on identifying steroid
structures and measuring steroid concentrations in body fluids. The molecular biology …