Osteopontin (OPN) is a ubiquitously expressed protein with a wide range of physiological
functions, including roles in bone mineralization, immune regulation, and wound healing …

Maintaining a balance between the supply and demand of oxygen is vital for proper organ
function. Most types of acute kidney injury (AKI) are characterized by hypoxia, a state where …

Aims Steatosis reducing effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors in non-
alcoholic steatohepatitis (NASH) has been consistently reported in humans, but their …

Background Classically activated M1 macrophages, characterized by aberrant glycolysis
and secretion of inflammatory cytokines, play pivotal roles in inflammatory diseases …

Aims To elucidate the association between baseline renal characteristics and the disparities
in renal outcomes among patients with SGLT2i treatment. Methods Pubmed, Medline …

Aims To evaluate the effects of initiating sodium‐glucose cotransporter‐2 (SGLT2) inhibitors
on cardiorenal outcomes and mortality compared to dipeptidyl peptidase‐4 (DPP‐4) …

This study aimed to evaluate the antidiabetic potential of compounds from Anogeissus
leiocarpus in silico and the potential of the compounds as antidiabetic drug candidates …

Objectives To validate the feasibility of intravoxel incoherent motion imaging (IVIM) for
monitoring renal injury and uric acid-lowering efficacy in a rat model of hyperuricaemia …

The benzoxazolone nucleus is an ideal scaffold for drug design, owing to its discrete
physicochemical profile, bioisosteric preference over pharmacokinetically weaker moieties …

Background: Although the clinical outcomes of diabetes have improved, diabetes remains
the principal cause of end-stage renal disease. The aim of the study is to investigate whether …