[HTML][HTML] Innate immune evasion strategies of SARS-CoV-2
JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …
and is more devastating than any other previous infectious disease. It has affected a …
[HTML][HTML] Pattern recognition receptors in health and diseases
D Li, M Wu - Signal transduction and targeted therapy, 2021 - nature.com
Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …
[HTML][HTML] SARS-CoV-2-specific immune response and the pathogenesis of COVID-19
E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
Adenovirus vector-based vaccine for infectious diseases
F Sakurai, M Tachibana, H Mizuguchi - Drug Metabolism and …, 2022 - Elsevier
Replication-incompetent adenovirus (Ad) vectors have been widely used as gene delivery
vehicles in both gene therapy studies and basic studies for gene function analysis due to …
vehicles in both gene therapy studies and basic studies for gene function analysis due to …
[HTML][HTML] Metformin to decrease COVID-19 severity and mortality: Molecular mechanisms and therapeutic potential
The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 has become a serious
challenge for medicine and science. Analysis of the molecular mechanisms associated with …
challenge for medicine and science. Analysis of the molecular mechanisms associated with …
[HTML][HTML] Mitochondrial DNA-triggered innate immune response: mechanisms and diseases
Various cellular stress conditions trigger mitochondrial DNA (mtDNA) release from
mitochondria into the cytosol. The released mtDNA is sensed by the cGAS-MITA/STING …
mitochondria into the cytosol. The released mtDNA is sensed by the cGAS-MITA/STING …
[HTML][HTML] African swine fever virus MGF360-14L negatively regulates type I interferon signaling by targeting IRF3
Y Wang, S Cui, T Xin, X Wang, H Yu, S Chen… - Frontiers in cellular …, 2022 - frontiersin.org
African swine fever (ASF) is a devastating infectious disease caused by African swine fever
virus (ASFV). The ASFV genome encodes multiple structural and non-structural proteins that …
virus (ASFV). The ASFV genome encodes multiple structural and non-structural proteins that …
[HTML][HTML] Innate immune responses to influenza virus infections in the upper respiratory tract
The innate immune system is the host's first line of immune defence against any invading
pathogen. To establish an infection in a human host the influenza virus must replicate in …
pathogen. To establish an infection in a human host the influenza virus must replicate in …
[HTML][HTML] DNA damage-induced inflammatory microenvironment and adult stem cell response
Adult stem cells ensure tissue homeostasis and regeneration after injury. Due to their
longevity and functional requirements, throughout their life stem cells are subject to a …
longevity and functional requirements, throughout their life stem cells are subject to a …