P El Meouchy, M Wahoud, S Allam, R Chedid… - International journal of …, 2022 - mdpi.com
The World Health Organization (WHO) refers to obesity as abnormal or excessive fat accumulation that presents a health risk. Obesity was first designated as a disease in 2012 …
F Ahangari, NL Price, S Malik, M Chioccioli… - JCI insight, 2023 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease. Recent findings have shown a marked metabolic reprogramming associated with changes in …
The global prevalence of nonalcoholic fatty liver disease (NAFLD) or metabolic associated fatty liver disease (MAFLD), as it is now known, has gradually increased. NAFLD is a …
G Saenz-Pipaon, DA Dichek - Atherosclerosis, 2023 - Elsevier
Discovered three decades ago, microRNAs (miRNAs) are now recognized as key players in the pathophysiology of multiple human diseases, including those affecting the …
S Jebari‐Benslaiman, KB Uribe, A Benito‐Vicente… - Small, 2022 - Wiley Online Library
Cardiovascular disease, the leading cause of mortality worldwide, is primarily caused by atherosclerosis, which is characterized by lipid and inflammatory cell accumulation in blood …
CL Galindo, S Khan, X Zhang, YS Yeh… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Lipid-laden foam cells within atherosclerotic plaques are key players in all phases of lesion development including its progression, necrotic core formation, fibrous cap …
Atherosclerotic cardiovascular disease (ASCVD) is one of the major leading global causes of death. Genetic and epidemiological studies strongly support the causal association …
IC Esobi, O Oladosu, J Echesabal-Chen… - Journal of …, 2023 - Wiley Online Library
Recent evidence suggests that the majority of cholesterol‐laden cells found in atherosclerotic lesions are vascular smooth muscle cells (VSMC) that have …
Atherogenic dyslipidemia plays a critical role in the development of metabolic syndrome (MetS), being one of its major components, along with central obesity, insulin resistance …