[HTML][HTML] A new paradigm is needed to explain long COVID

C Saunders, S Sperling, E Bendstrup - The Lancet Respiratory …, 2023 - thelancet.com
We now have adequate data to describe the core symptoms, course, and prevalence of long
COVID. Core symptoms include breathing difficulties, muscle pain, anosmia, tingling …

[HTML][HTML] Mucosal immunity: The missing link in comprehending SARS-CoV-2 infection and transmission

MW Russell, J Mestecky - Frontiers in immunology, 2022 - frontiersin.org
SARS-CoV-2 is primarily an airborne infection of the upper respiratory tract, which on
reaching the lungs causes the severe acute respiratory disease, COVID-19. Its first contact …

Depleting myeloid-biased haematopoietic stem cells rejuvenates aged immunity

JB Ross, LM Myers, JJ Noh, MM Collins, AB Carmody… - Nature, 2024 - nature.com
Ageing of the immune system is characterized by decreased lymphopoiesis and adaptive
immunity, and increased inflammation and myeloid pathologies,. Age-related changes in …

Molnupiravir and risk of post-acute sequelae of covid-19: cohort study

Y Xie, T Choi, Z Al-Aly - bmj, 2023 - bmj.com
Objective To examine whether treatment with the antiviral agent molnupiravir during the first
five days of SARS-CoV-2 infection is associated with reduced risk of post-acute adverse …

[PDF][PDF] Anatomical barriers against SARS-CoV-2 neuroinvasion at vulnerable interfaces visualized in deceased COVID-19 patients

M Khan, M Clijsters, S Choi, W Backaert, M Claerhout… - Neuron, 2022 - cell.com
Can SARS-CoV-2 hitchhike on the olfactory projection and take a direct and short route from
the nose into the brain? We reasoned that the neurotropic or neuroinvasive capacity of the …

Thrombo-inflammation in long COVID–the elusive key to post-infection sequelae?

L Nicolai, R Kaiser, K Stark - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Long COVID is a public health emergency affecting millions of people worldwide,
characterized by heterogenous symptoms across multiple organs systems. Here, we discuss …

Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single …

M Tosato, R Calvani, A Picca, F Ciciarello, V Galluzzo… - Nutrients, 2022 - mdpi.com
Long COVID, a condition characterized by symptom and/or sign persistence following an
acute COVID-19 episode, is associated with reduced physical performance and endothelial …

Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …

COVID-19 and liver disease

JF Dufour, T Marjot, C Becchetti, H Tilg - Gut, 2022 - gut.bmj.com
Knowledge on SARS-CoV-2 infection and its resultant COVID-19 in liver diseases has
rapidly increased during the pandemic. Hereby, we review COVID-19 liver manifestations …

Nirmatrelvir and the risk of post-acute sequelae of COVID-19

Y Xie, T Choi, Z Al-Aly - MedRxiv, 2022 - medrxiv.org
Long Covid–the disease encompassing the post-acute sequelae of SARS-CoV-2 (PASC)—
affects millions of people around the world. Prevention of PASC is an urgent public health …