An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

Infection with SARS-CoV-2 results in clinical outcomes ranging from silent or benign
infection in most individuals to critical pneumonia and death in a few. Genetic studies in …

Disclosures: C. Flores reported grants from Instituto de Salud Carlos III, Spanish Ministry of
Science and Innovation, and Cabildo Insular de Tenerife outside the submitted work. J …

Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

Coronavirus disease 2019 in children presents with milder clinical manifestations than in
adults. On the other hand, the presence of a wide range of inflammatory manifestations …

The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …

We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19
pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-α2 in 10 patients …

Type I IFNs, a family of cytokines that signal through a single receptor and signaling
mechanism, were originally named for their ability to interfere with viral replication. While …

The phylum Nucleocytoviricota includes the largest and most complex viruses known. These
“giant viruses” have a long evolutionary history that dates back to the early diversification of …

Introduction Long COVID is a chronic condition that follows after acute COVID-19 and is
characterized by a wide range of persistent, cyclic symptoms. Sources of data PubMed …