Next generation sequencing (NGS) has provided biologists with an unprecedented view into
biological processes and their regulation over the past 2 decades, fueling a wave of …

Genomic imprinting refers to the parent-of-origin expression of genes, which originates from
epigenetic events in the mammalian germ line. The evolution of imprinting may reflect a …

Long single-molecular sequencing technologies, such as PacBio circular consensus
sequencing (CCS) and nanopore sequencing, are advantageous in detecting DNA 5 …

Less than half of individuals with a suspected Mendelian condition receive a precise
molecular diagnosis after comprehensive clinical genetic testing. Improvements in data …

Combining genome assembly with population and functional genomics can provide
valuable insights to development and evolution, as well as tools for species management …

Hundreds of loci in human genomes have alleles that are methylated differentially according
to their parent of origin. These imprinted loci generally show little variation across tissues …

Five years on from our award-winning review on Nextgeneration sequencing and emerging
technologies, 1 a rapid pace of fundamental advances has markedly altered the landscape …

Pore-forming proteins (PFPs) are a broad class of molecules that comprise various families,
structural folds, and assembly pathways. In nature, PFPs are most often deployed by their …

Genomic imprinting represents an original model of epigenetic regulation resulting in a
parent-of-origin expression. Despite the critical role of imprinted genes in mammalian …

Pallas's cat, or the manul cat (Otocolobus manul), is a small felid native to the grasslands
and steppes of central Asia. Population strongholds in Mongolia and China face growing …