IL-1β and the intestinal epithelial tight junction barrier

LW Kaminsky, R Al-Sadi, TY Ma - Frontiers in immunology, 2021 - frontiersin.org
The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of
contents from the intestinal lumen into the intestinal tissue and systemic circulation. A …

Food components and dietary habits: keys for a healthy gut microbiota composition

E Rinninella, M Cintoni, P Raoul, LR Lopetuso… - Nutrients, 2019 - mdpi.com
The gut microbiota is a changing ecosystem, containing trillions of bacteria, continuously
shaped by many factors, such as dietary habits, seasonality, lifestyle, stress, antibiotics use …

How do intestinal probiotics restore the intestinal barrier?

HZ Gou, YL Zhang, LF Ren, ZJ Li, L Zhang - Frontiers in microbiology, 2022 - frontiersin.org
The intestinal barrier is a structure that prevents harmful substances, such as bacteria and
endotoxins, from penetrating the intestinal wall and entering human tissues, organs, and …

[HTML][HTML] Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut

Y Deng, Z Yan, R Shen, M Wang, Y Huang… - Environment …, 2020 - Elsevier
Increasing evidence shows that microplastics (MPs) have the potential to act as carriers and
transport contaminants into organisms, as well as induce serious health risks. Here we …

Understanding the physiology of human defaecation and disorders of continence and evacuation

PT Heitmann, PF Vollebregt, CH Knowles… - Nature reviews …, 2021 - nature.com
The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Gut microbiome and aging: Physiological and mechanistic insights

R Nagpal, R Mainali, S Ahmadi, S Wang… - … and healthy aging, 2018 - content.iospress.com
The development of human gut microbiota begins as soon as the neonate leaves the
protective environment of the uterus (or maybe in-utero) and is exposed to innumerable …

[HTML][HTML] Gastrointestinal tract (gut) health in the young pig

JR Pluske, DL Turpin, JC Kim - Animal Nutrition, 2018 - Elsevier
An optimally functioning gastrointestinal tract (GIT) clearly is of importance to the overall
metabolism, physiology, disease status and performance of pigs of all stages of growth and …

Gut/brain axis and the microbiota

EA Mayer, K Tillisch, A Gupta - The Journal of clinical …, 2015 - Am Soc Clin Investig
Tremendous progress has been made in characterizing the bidirectional interactions
between the central nervous system, the enteric nervous system, and the gastrointestinal …

Intestinal permeability–a new target for disease prevention and therapy

SC Bischoff, G Barbara, W Buurman, T Ockhuizen… - BMC …, 2014 - Springer
Data are accumulating that emphasize the important role of the intestinal barrier and
intestinal permeability for health and disease. However, these terms are poorly defined, their …

Dysbiosis of Gram‑negative gut microbiota and the associated serum lipopolysaccharide exacerbates inflammation in type 2 diabetic patients with chronic kidney …

MV Salguero, MAI Al‑Obaide… - Experimental and …, 2019 - spandidos-publications.com
Lipopolysaccharide (LPS), a potent endotoxin present in the outer membrane of Gram‑
negative bacteria, causes chronic immune responses associated with inflammation. In the …