This review commemorates the 40th anniversary of DNA sequencing, a period in which we have already witnessed multiple technological revolutions and a growth in scale from a few …
LR Nassar, GP Barber, A Benet-Pagès… - Nucleic acids …, 2023 - academic.oup.com
Abstract The UCSC Genome Browser (https://genome. ucsc. edu) is an omics data consolidator, graphical viewer, and general bioinformatics resource that continues to serve …
Mapping single-cell sequencing profiles to comprehensive reference datasets provides a powerful alternative to unsupervised analysis. However, most reference datasets are …
The human Y chromosome has been notoriously difficult to sequence and assemble because of its complex repeat structure that includes long palindromes, tandem repeats and …
N Li, Q He, J Wang, B Wang, J Zhao, S Huang… - Nature Genetics, 2023 - nature.com
Effective utilization of wild relatives is key to overcoming challenges in genetic improvement of cultivated tomato, which has a narrow genetic basis; however, current efforts to decipher …
Mutations in non-coding regulatory DNA sequences can alter gene expression, organismal phenotype and fitness,–. Constructing complete fitness landscapes, in which DNA …
Meningiomas are the most common primary intracranial tumour in adults. Patients with symptoms are generally treated with surgery as there are no effective medical therapies. The …
P Davis, M Zarowiecki, V Arnaboldi, A Becerra… - Genetics, 2022 - academic.oup.com
Abstract WormBase (www. wormbase. org) is the central repository for the genetics and genomics of the nematode Caenorhabditis elegans. We provide the research community …
Advances in genomics have expedited the improvement of several agriculturally important crops but similar efforts in wheat (Triticum spp.) have been more challenging. This is largely …