Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

Background Recent research on the implications of gut microbiota on brain functions has
helped to gather important information on the relationship between them. Pathogenesis of …

Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

Nonalcoholic fatty liver disease (NAFLD), affecting about 25% of general population and
more than 50% of dysmetabolic patients, is an emerging cause of chronic liver disease and …

Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …

Ubiquitin signaling is a conserved, widespread, and dynamic process in which protein
substrates are rapidly modified by ubiquitin to impact protein activity, localization, or stability …

Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …

Protein aggregation causes α-synuclein to switch from its physiological role to a pathological
toxic gain of function. Under physiological conditions, monomeric α-synuclein improves ATP …