Methods to improve the immunogenicity of plasmid DNA vaccines

D Eusébio, AR Neves, D Costa, S Biswas, G Alves… - Drug Discovery …, 2021 - Elsevier
DNA vaccines have emerged as innovative approaches that have great potential to
overcome the limitations of current conventional vaccines. Plasmid DNA vaccines are often …

[HTML][HTML] Baseline mapping of severe fever with thrombocytopenia syndrome virology, epidemiology and vaccine research and development

NE Bopp, JA Kaiser, AE Strother, ADT Barrett… - NPJ vaccines, 2020 - nature.com
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly emergent tick-borne
bunyavirus first discovered in 2009 in China. SFTSV is a growing public health problem that …

Fatal outcome of severe fever with thrombocytopenia syndrome (SFTS) and severe and critical COVID‐19 is associated with the hyperproduction of IL‐10 and IL‐6 …

SY Kang, JR Yoo, Y Park, SH Kim… - Journal of Medical …, 2023 - Wiley Online Library
Severe fever with thrombocytopenia syndrome virus (SFTSV) and severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) can cause the hyperproduction of inflammatory …

[HTML][HTML] Emerging Tick-Borne Dabie bandavirus: Virology, Epidemiology, and Prevention

EH Kim, SJ Park - Microorganisms, 2023 - mdpi.com
Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by Dabie bandavirus
(SFTSV), is an emerging infectious disease first identified in China. Since its discovery …

[HTML][HTML] Immune escape mechanisms of severe fever with thrombocytopenia syndrome virus

T Wang, L Xu, B Zhu, J Wang, X Zheng - Frontiers in Immunology, 2022 - frontiersin.org
Severe fever with thrombocytopenia syndrome (SFTS), which is caused by SFTS virus
(SFTSV), poses a serious threat to global public health, with high fatalities and an increasing …

[HTML][HTML] Animal model of severe fever with thrombocytopenia syndrome virus infection

J Sun, YQ Min, Y Li, X Sun, F Deng, H Wang… - Frontiers in …, 2022 - frontiersin.org
Severe fever with thrombocytopenia syndrome (SFTS), an emerging life-threatening
infectious disease caused by SFTS bunyavirus (SFTSV; genus Bandavirus, family …

[HTML][HTML] mRNA vaccine encoding Gn provides protection against severe fever with thrombocytopenia syndrome virus in mice

JY Kim, K Jeon, SI Park, YJ Bang, HJ Park, HW Kwak… - npj Vaccines, 2023 - nature.com
We developed a promising mRNA vaccine against severe fever with thrombocytopenia
syndrome (SFTS), an infectious disease caused by the SFTS virus that is primarily …

[HTML][HTML] An mRNA-Based Multiple Antigenic Gene Expression System Delivered by Engineered Salmonella for Severe Fever with Thrombocytopenia Syndrome and …

JY Park, C Hewawaduge, C Sivasankar, KKS Lloren… - Pharmaceutics, 2023 - mdpi.com
Currently, there are no commercial vaccines or therapeutics against severe fever with
thrombocytopenia syndrome (SFTS) virus. This study explored an engineered Salmonella …

[HTML][HTML] Heterologous vaccination utilizing viral vector and protein platforms confers complete protection against SFTSV

JY Kim, K Jeon, JJ Hong, SI Park, H Cho, HJ Park… - Scientific Reports, 2023 - nature.com
Severe fever with thrombocytopenia syndrome virus was first discovered in 2009 as the
causative agent of severe fever with thrombocytopenia syndrome. Despite its potential threat …

A natural variation in the RNA polymerase of severe fever with thrombocytopenia syndrome virus enhances viral replication and in vivo virulence

K Jeon, HJ Ro, JG Kang, DE Jeong… - Journal of Medical …, 2023 - Wiley Online Library
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick‐borne disease
with high mortality in Eastern Asia. The disease is caused by the SFTS virus (SFTSV), also …