The COVID-19 pandemic caused by SARS-CoV-2 has posed unparalleled challenges due
to its rapid transmission, ability to mutate, high mortality and morbidity, and enduring health …

Experimental work with viruses that are highly pathogenic for humans and animals requires
specialized Biosafety Level 3 or 4 facilities. Such pathogens include some spectacular but …

Abstract Multiple FDA-approved SARS-CoV-2 vaccines currently provide excellent
protection against severe disease. Despite this, immunity can wane relatively fast …

Viruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), use
respiratory epithelial cells as an entry point for infection. Within the nasal cavity, the olfactory …

Here we investigated the virulence properties of a unique cell-adapted SARS-CoV-2 mutant
showing a ten-amino acid deletion encompassing the furin cleavage site of the spike protein …

In the study of transgenic mouse models of neurodevelopmental and neurodegenerative
disorders, we use batteries of tests to measure deficits in behaviour and from the results of …

Potential nonameric epitopes of CD8+ T lymphocytes were selected from the composition of
structural, accessory, and nonstructural proteins of the SARS-CoV-2 virus (13 peptides) and …

Potential nonameric epitopes of CD8+ T lymphocytes were selected from the composition of
structural, accessory, and non-structural proteins of SARS-CoV-2 virus (13 peptides) and a …

Crimean-Congo hemorrhagic fever virus (CCHFV) is an important tick-borne human
pathogen endemic throughout Asia, Africa and Europe. The pathogenic mechanisms of …

Ever since the appearance of COVID-19, the pathophysiology of SARS-CoV2 infection, the
identification of treatments and the development of vaccines have been priorities. This …