The Human Genome Project was an enormous accomplishment, providing a foundation for
countless explorations into the genetics and genomics of the human species. Yet for many …

In the era of precision medicine, genome sequencing (GS) has become more affordable and
the importance of genomics and multi-omics in clinical care is increasingly being …

Long-read sequencing (LRS) technology along with the recent development of
computational tools, crowned the ''method of the year 2022''(Marx, 2023), have made it …

Recent studies have shown that the noncoding genome can produce unannotated proteins
as antigens that induce immune response. One major source of this activity is the aberrant …

Mapping transcriptomic variations using either short-or long-read RNA sequencing is a
staple of genomic research. Long reads are able to capture entire isoforms and overcome …

The coverage of the protein database directly determines the results of shotgun proteomics.
In this study, PacBio single-molecule real-time sequencing technology was performed on …

Arabidopsis thaliana diverged from A. arenosa and A. lyrata at least 6 million years ago. The
three species differ by genome‐wide polymorphisms and morphological traits. The species …

Plant mitochondrial and plastid genomes typically show pervasive, genome-wide
transcription. Little is known, however, about the utility of organelle noncoding RNAs, which …

Structural variants (SVs)—including duplications, deletions, and inversions of DNA—can
have significant genomic and functional impacts but are technically difficult to identify and …

Transposable elements (TEs) are genomic parasites found in nearly all eukaryotes,
including humans. This evolutionary success of TEs is due to their replicative activity …