Human Pavlovian fear conditioning conforms to probabilistic learning

A Tzovara, CW Korn, DR Bach - PLoS computational biology, 2018 - journals.plos.org
Learning to predict threat from environmental cues is a fundamental skill in changing
environments. This aversive learning process is exemplified by Pavlovian threat …

[HTML][HTML] Learning dynamics of electrophysiological brain signals during human fear conditioning

MFJ Sperl, A Wroblewski, M Mueller, B Straube… - NeuroImage, 2021 - Elsevier
Electrophysiological studies in rodents allow recording neural activity during threats with
high temporal and spatial precision. Although fMRI has helped translate insights about the …

A pupil size response model to assess fear learning

CW Korn, M Staib, A Tzovara, G Castegnetti… - …, 2017 - Wiley Online Library
During fear conditioning, pupil size responses dissociate between conditioned stimuli that
are contingently paired (CS+) with an aversive unconditioned stimulus, and those that are …

Critical evaluation of current data analysis strategies for psychophysiological measures of fear conditioning and extinction in humans

LJ Ney, M Wade, A Reynolds, DV Zuj, S Dymond… - International Journal of …, 2018 - Elsevier
Fear conditioning and extinction is a construct integral to understanding trauma-, stress-and
anxiety-related disorders. In the laboratory, associative learning paradigms that pair …

A mixed filter algorithm for sympathetic arousal tracking from skin conductance and heart rate measurements in Pavlovian fear conditioning

DS Wickramasuriya, RT Faghih - PloS one, 2020 - journals.plos.org
Pathological fear and anxiety disorders can have debilitating impacts on individual patients
and society. The neural circuitry underlying fear learning and extinction has been known to …

Postural freezing relates to startle potentiation in a human fear‐conditioning paradigm

VA van Ast, F Klumpers, RPPP Grasman… - …, 2022 - Wiley Online Library
Freezing to impending threat is a core defensive response. It has been studied primarily
using fear conditioning in non‐human animals, thwarting advances in translational human …

Pupil dilation as an implicit measure of appetitive Pavlovian learning

C Pietrock, C Ebrahimi, TM Katthagen… - …, 2019 - Wiley Online Library
Appetitive Pavlovian conditioning is a learning mechanism of fundamental biological and
pathophysiological significance. Nonetheless, its exploration in humans remains sparse …

Aversive contexts enhance defensive responses to conditioned threat

Y Stegmann, J Paulus, MJ Wieser… - Psychophysiology, 2023 - Wiley Online Library
The ability to flexibly transition between defensive states is crucial for adaptive responding in
life‐threatening situations. Potentially threatening situations typically induce a sustained …

Modeling startle eyeblink electromyogram to assess fear learning

S Khemka, A Tzovara, S Gerster… - …, 2017 - Wiley Online Library
Pavlovian fear conditioning is widely used as a laboratory model of associative learning in
human and nonhuman species. In this model, an organism is trained to predict an aversive …

Atypical response to affective touch in children with autism: multi-parametric exploration of the autonomic system

MR Bufo, M Guidotti, Y Mofid, J Malvy… - Journal of Clinical …, 2022 - mdpi.com
This study aimed at evaluating the autonomic response to pleasant affective touch in
children with Autism Spectrum Disorders (ASD) and age-matched typically developing (TD) …