Dry eye disease (DED) is a multifactorial disorder characterized by loss of tear film
homeostasis with an estimated worldwide prevalence of 5% to 50%. In DED, dysfunction of …

Retinal ganglion cells (RGCs) play a crucial role in the visual pathway. As their axons form
the optic nerve, apoptosis of these cells causes neurodegenerative vision loss. RGC death …

Diabetic keratopathy (DK) is a common, but underdiagnosed, ocular complication of
diabetes mellitus (DM) that has a significant economic burden. It is characterised by …

Neurotrophic keratopathy (NK), or neurotrophic keratitis, is a degenerative condition that
results from decreased innervation to the cornea. The cornea is innervated by the …

Dry eye disease (DED) is a multifactorial disease of the ocular surface system whose chore
mechanisms are tear film instability, inflammation, tear hyperosmolarity and epithelial …

Neurotrophic keratitis is an underdiagnosed degenerative condition induced by impairment
to the corneal nerves which may lead to persistent epithelial defects and corneal blindness …

Cenegermin (Oxervate™), an ophthalmic solution containing 20 µg/mL of recombinant
human nerve growth factor (rhNGF), is the first drug to be approved for the treatment of …

Lactoferrin is a naturally occurring iron-binding glycoprotein, produced and secreted by
mucosal epithelial cells and neutrophils in various mammalian species, including humans. It …

Background Neurotrophic keratopathy (NK) is a relatively uncommon, underdiagnosed
degenerative corneal disease that is caused by damage to the ophthalmic branch of the …

Keratitis is one of the most prevalent ocular diseases manifested by partial or total loss of
vision. Amongst infectious (viz., microbes including bacteria, fungi, amebae, and viruses) …