Hypermobility involves excessive flexibility and systemic manifestations of connective tissue
fragility. We propose a folate-dependent hypermobility syndrome model based on clinical …

Autism, also known as an autism spectrum disorder, is a complex neurodevelopmental
disorder usually diagnosed in the first three years of a child's life. A range of symptoms …

The present study reports the development and application of a novel, sensitive, and
selective voltammetric sensor for the quantitation of folate or vitamin B9 in foodstuffs. The …

This review delves into the intricate relationship between excess folate (vitamin B9) intake,
especially its synthetic form, namely, folic acid, and its implications on health and disease …

Inadequate folate intake during pregnancy is the leading cause of the development of neural
tube defects (NTDs) in newborns. For this reason, mandatory fortification of folic acid, a …

The brain has high energy demand making it sensitive to changes in energy fuel supply.
Aging shrinks brain volume, decreases glucose uptake availability of the brain, and finally …

The rationale and importance of folic acid supplementation during pregnancy for fetal
congenital defect prevention are accepted worldwide. Moreover, a sufficient plasma …

Neural tube defects (NTDs) are the second most common congenital malformations of
humans, characterized by impaired development of the central nervous system. Even …

Hepatocellular carcinoma (HCC), which is a primary liver cancer subtype, has a poor
prognosis due to its high degree of malignancy. The lack of early diagnosis makes systemic …

Maintaining optimal one-carbon metabolism (OCM) is essential for health and pregnancy. In
this cross-sectional study, folate status was assessed based on 5-methyltetrahydrofolate (5 …