Breaking the barriers: the role of gut homeostasis in Metabolic-Associated Steatotic Liver Disease (MASLD)

R Benedé-Ubieto, FJ Cubero, YA Nevzorova - Gut microbes, 2024 - Taylor & Francis
ABSTRACT Obesity, insulin resistance (IR), and the gut microbiome intricately interplay in
Metabolic-associated Steatotic Liver Disease (MASLD), previously known as Non-Alcoholic …

Clinical Perspectives of Gut Microbiota in Patients with Chronic Kidney Disease and End-Stage Kidney Disease: Where Do We Stand?

AC Pantazi, MAK Kassim, W Nori, LA Tuta, CM Mihai… - Biomedicines, 2023 - mdpi.com
The gut microbiota (GM) plays a vital role in human health, with increasing evidence linking
its imbalance to chronic kidney disease and end-stage kidney disease. Although the exact …

Potential of postbiotics for the treatment of metabolic disorders

N Mishra, A Garg, S Ashique, S Bhatt - Drug Discovery Today, 2024 - Elsevier
Postbiotics, the next generation of probiotics, are extracts that are free of living and
nonviable bacteria and show strong modulatory effects on the gut flora. Examples include …

High glucose exposure drives intestinal barrier dysfunction by altering its morphological, structural and functional properties

N Dubois, J Muñoz-Garcia, D Heymann… - Biochemical …, 2023 - Elsevier
High dietary glucose consumption and hyperglycemia can result in chronic complications.
Several studies suggest that high glucose (HG) induces dysfunction of the intestinal barrier …

Microbiota dynamics preceding bariatric surgery as obesity treatment: a comprehensive review

AK Zambrano, E Paz-Cruz, VA Ruiz-Pozo… - Frontiers in …, 2024 - frontiersin.org
The review present data on the intricate relationship between bariatric surgery, gut
microbiota, and metabolic health in obesity treatment. Bariatric surgery, is recognized as an …

Piezo channels in the intestinal tract

H He, J Zhou, X Xu, P Zhou, H Zhong, M Liu - Frontiers in Physiology, 2024 - frontiersin.org
The intestine is the largest mechanosensitive organ in the human body whose epithelial
cells, smooth muscle cells, neurons and enteroendocrine cells must sense and respond to …

[HTML][HTML] Influence of dietary status on the obesogenic effects of erythromycin antibiotic on Caenorhabditis elegans

Z Li, Z Yu, D Yin - Environment International, 2024 - Elsevier
As emerging pollutants, antibiotics were widely detected in water bodies and dietary
sources. Recently, their obesogenic effects raised serious concerns. So far, it remained …

Cefotaxime Exposure-Caused Oxidative Stress, Intestinal Damage and Gut Microbial Disruption in Artemia sinica

H Pang, K Zheng, W Wang, M Zheng, Y Liu, H Yin… - Microorganisms, 2024 - mdpi.com
Cefotaxime (CTX) is an easily detectable antibiotic pollutant in the water environment, but
little is known about its toxic effects on aquatic invertebrates, especially on the intestine …

View on Metformin: Antidiabetic and Pleiotropic Effects, Pharmacokinetics, Side Effects, and Sex-Related Differences

G Froldi - Pharmaceuticals, 2024 - mdpi.com
Metformin is a synthetic biguanide used as an antidiabetic drug in type 2 diabetes mellitus,
achieved by studying the bioactive metabolites of Galega officinalis L. It is also used off-label …

Tomato seed extract promotes health of the gut microbiota and demonstrates a potential new way to valorize tomato waste

J Firrman, A Narrowe, LS Liu, K Mahalak, J Lemons… - Plos one, 2024 - journals.plos.org
The current effort to valorize waste byproducts to increase sustainability and reduce
agricultural loss has stimulated interest in potential utilization of waste components as health …