Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …
The role of NO in COVID-19 and potential therapeutic strategies
Nitric oxide (NO) is a free radical playing an important pathophysiological role in
cardiovascular and immune systems. Recent studies reported that NO levels were …
cardiovascular and immune systems. Recent studies reported that NO levels were …
Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome
LYC Chen, RL Hoiland, S Stukas… - European …, 2020 - Eur Respiratory Soc
The concept of coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome
(COVID-CSS) emerged early in the severe acute respiratory syndrome coronavirus 2 (SARS …
(COVID-CSS) emerged early in the severe acute respiratory syndrome coronavirus 2 (SARS …
Into the eye of the cytokine storm
JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
The cytokine storm has captured the attention of the public and the scientific community
alike, and while the general notion of an excessive or uncontrolled release of …
alike, and while the general notion of an excessive or uncontrolled release of …
New fronts emerge in the influenza cytokine storm
XJ Guo, PG Thomas - Seminars in immunopathology, 2017 - Springer
Influenza virus is a significant pathogen in humans and animals with the ability to cause
extensive morbidity and mortality. Exuberant immune responses induced following infection …
extensive morbidity and mortality. Exuberant immune responses induced following infection …
The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19
Abstract The coronavirus disease (COVID-19) has once again reminded us of the
significance of host immune response and consequential havocs of the immune …
significance of host immune response and consequential havocs of the immune …
[HTML][HTML] The safety and side effects of monoclonal antibodies
TT Hansel, H Kropshofer, T Singer, JA Mitchell… - Nature reviews Drug …, 2010 - nature.com
Monoclonal antibodies (mAbs) are now established as targeted therapies for malignancies,
transplant rejection, autoimmune and infectious diseases, as well as a range of new …
transplant rejection, autoimmune and infectious diseases, as well as a range of new …
Modulating immunity as a therapy for bacterial infections
REW Hancock, A Nijnik, DJ Philpott - Nature Reviews Microbiology, 2012 - nature.com
Despite our efforts to halt the increase and spread of antimicrobial resistance, bacteria
continue to become less susceptible to antimicrobial drugs over time, and rates of discovery …
continue to become less susceptible to antimicrobial drugs over time, and rates of discovery …
Programmed ageing: decline of stem cell renewal, immunosenescence, and Alzheimer's disease
R Lathe, D St. Clair - Biological Reviews, 2023 - Wiley Online Library
The characteristic maximum lifespan varies enormously across animal species from a few
hours to hundreds of years. This argues that maximum lifespan, and the ageing process that …
hours to hundreds of years. This argues that maximum lifespan, and the ageing process that …
[HTML][HTML] Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective
C Lee, WJ Choi - Archives of pharmacal research, 2021 - Springer
The novel beta coronavirus (SARS-CoV-2, designated as COVID-19) that is responsible for
severe acute respiratory syndrome has devastated the global economy and health care …
severe acute respiratory syndrome has devastated the global economy and health care …