Although interest and funding in nanotechnology for oncological applications is thriving,
translating these novel therapeutics through the earliest stages of preclinical assessment …

Nanobiomaterials have been widely accepted as potential drug delivery agents over the
past decade. A wide variety of materials have been utilized as drug delivery carriers for …

Zoonotic viruses that emerge from wildlife and domesticated animals pose a serious threat
to human and animal health. In many instances, mouse models have improved our …

Although often encoding fewer than a dozen genes, RNA viruses can overcome host
antiviral responses and wreak havoc on the cells they infect. Some manage to evade host …

The term cytokine storm has become a popular descriptor of the dramatic harmful
consequences of the rapid release of polypeptide mediators, or cytokines, that generate …

Immune therapy to ease the burden of sepsis has thus far failed to consistently improve
patient outcomes. Advances in cancer immune therapy and awareness that prolonged …

Innate and adaptive immune responses have a well-known link and represent the distinctive
origins of several diseases, many of which may be the consequence of the loss of balance …

In the global health emergency caused by coronavirus disease 2019 (COVID-19), efficient
and specific therapies are urgently needed. Compared with traditional small-molecular …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Wuhan,
China has dispersed rapidly worldwide. Although most patients present with mild fever …

Malaria is a highly inflammatory disease caused by Plasmodium infection of host
erythrocytes. However, the parasite does not induce inflammatory cytokine responses in …