[HTML][HTML] Water extract of Artemisia scoparia Waldst. & Kitam suppresses LPS-induced cytokine production and NLRP3 inflammasome activation in macrophages and …

JH Ahn, YL Park, AY Song, WG Kim, CY Je… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Artemisia scoparia Waldst. & Kitam (A. scoparia)
is a perennial herbal plant that is widely used as a folk remedy in Asian countries. Several …

[HTML][HTML] The cross-species immunity during acute Babesia co-infection in mice

I Zafar, EM Galon, D Kondoh, A Efstratiou… - Frontiers in Cellular …, 2022 - frontiersin.org
Babesiosis causes high morbidity and mortality in immunocompromised individuals. An
earlier study suggested that lethal Babesia rodhaini infection in murine can be evaded by …

[HTML][HTML] PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1

L Wang, Y Zhou, Z Chen, L Sun, J Wu, H Li… - Nature …, 2019 - nature.com
Excessive or uncontrolled release of proinflammatory cytokines caused by severe viral
infections often results in host tissue injury or even death. Phospholipase C (PLC) s degrade …

Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: possible implication in parkinson′ s disease …

A Machado, AJ Herrera, JL Venero… - Parkinson's …, 2011 - Wiley Online Library
Inflammatory processes described in Parkinson's disease (PD) and its animal models
appear to be important in the progression of the pathogenesis, or even a triggering factor …

Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant

LO Mosnier, A Zampolli, EJ Kerschen… - Blood, The Journal …, 2009 - ashpublications.org
Activated protein C (APC) reduces mortality in severe sepsis patients. APC exerts
anticoagulant activities via inactivation of factors Va and VIIIa and cytoprotective activities via …

[HTML][HTML] Three amino acid substitutions in the NS1 protein change the virus replication of H5N1 influenza virus in human cells

J Li, K Zhang, Q Chen, X Zhang, Y Sun, Y Bi, S Zhang… - Virology, 2018 - Elsevier
Influenza A viruses have sophisticated strategies to promote their own replication. Here, we
found that three H5N1 influenza viruses display different replication patterns in human A549 …

Sex-dependent differences in plasma cytokine responses to hantavirus infection

J Klingström, T Lindgren, C Ahlm - Clinical and Vaccine …, 2008 - Am Soc Microbiol
There are often sex differences in susceptibility to infectious diseases and in level of
mortality after infection. These differences probably stem from sex-related abilities to mount …

Kinetics of the inflammatory response during experimental Babesia rossi infection of beagle dogs

BK Atkinson, P Thompson, E Van Zyl, A Goddard… - Veterinary …, 2022 - Elsevier
Babesia rossi causes severe morbidity and mortality in dogs in sub-Saharan Africa, and the
complications associated with this disease are likely caused by an unfocused, excessive …

Background to new treatments for COVID‐19, including its chronicity, through altering elements of the cytokine storm

IA Clark - Reviews in Medical Virology, 2021 - Wiley Online Library
Anti‐tumour necrosis factor (TNF) biologicals, Dexamethasone and rIL‐7 are of
considerable interest in treating COVID‐19 patients who are in danger of, or have become …

[HTML][HTML] Multiple and simultaneous detection for cytokines based on the nanohole array by electrochemical sandwich immunoassay

HN Suh, SH Yoon, YM Park, HJ Kim, SH Kim… - … and Bioelectronics: X, 2023 - Elsevier
Monitoring of cytokine storm markers is critical for determining the disease progression and
treatment efficacy. In this study, we developed a novel fourplex electrochemical (EC) …