[HTML][HTML] Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

[HTML][HTML] COVID-19-associated fungal infections

M Hoenigl, D Seidel, R Sprute, C Cunha… - Nature …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an
important complication in a substantial number of critically ill, hospitalized patients with …

[HTML][HTML] SARS-CoV-2 infection and persistence in the human body and brain at autopsy

SR Stein, SC Ramelli, A Grazioli, JY Chung, M Singh… - Nature, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction,–
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection

M Patone, XW Mei, L Handunnetthi, S Dixon… - Nature medicine, 2022 - nature.com
Although myocarditis and pericarditis were not observed as adverse events in coronavirus
disease 2019 (COVID-19) vaccine trials, there have been numerous reports of suspected …

[HTML][HTML] Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group - Lancet (London, England), 2021 - ncbi.nlm.nih.gov
Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients
admitted to hospital with COVID-19 with both hypoxia and systemic inflammation. Methods …

[HTML][HTML] Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2021 - thelancet.com
Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients
admitted to hospital with COVID-19 with both hypoxia and systemic inflammation. Methods …

COVID-19 and cardiovascular disease: from bench to bedside

MK Chung, DA Zidar, MR Bristow, SJ Cameron… - Circulation …, 2021 - Am Heart Assoc
A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential
consequences on the cardiovascular health of millions of people who survive infection …

[HTML][HTML] Genetic mechanisms of critical illness in COVID-19

E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick… - Nature, 2021 - nature.com
Host-mediated lung inflammation is present, and drives mortality, in the critical illness
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - Medrxiv, 2021 - medrxiv.org
Background REGEN-COV is a combination of 2 monoclonal antibodies (casirivimab and
imdevimab) that bind to two different sites on the receptor binding domain of the SARS-CoV …

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): preliminary results of a randomised, controlled, open-label, platform trial

PW Horby, G Pessoa-Amorim, L Peto, CE Brightling… - Medrxiv, 2021 - medrxiv.org
Background Tocilizumab is a monoclonal antibody that binds to the receptor for interleukin
(IL)-6, reducing inflammation, and is commonly used to treat rheumatoid arthritis. We …