Essential role of CCR2 in neutrophil tissue infiltration and multiple organ dysfunction in sepsis

FO Souto, JC Alves-Filho, WM Turato… - American journal of …, 2011 - atsjournals.org
Rationale: Sepsis is defined as a systemic inflammatory response to infection, which in its
severe form is associated with multiple organ dysfunction syndrome (MODS). The precise …

[HTML][HTML] Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized …

VM Barbosa, EA Miles, C Calhau, E Lafuente… - Critical Care, 2010 - Springer
Introduction The effect of parenteral fish oil in septic patients is not widely studied. This study
investigated the effects of parenteral fish oil on plasma phospholipid fatty acids …

Viral load and cytokine response profile does not support antibody-dependent enhancement in dengue-primed Zika virus–infected patients

ACB Terzian, AS Schanoski, MTO Mota… - Clinical Infectious …, 2017 - academic.oup.com
Background The pathogenesis of severe dengue disease involves immune components as
biomarkers. The mechanism by which some dengue virus (DENV)–infected individuals …

Identification of procathepsin L (pCTS-L)–neutralizing monoclonal antibodies to treat potentially lethal sepsis

CS Zhu, X Qiang, W Chen, J Li, X Lan, H Yang… - Science …, 2023 - science.org
Antibody-based strategies have been attempted to antagonize early cytokines of sepsis, but
not yet been tried to target inducible late-acting mediators. Here, we report that the …

Clinical manifestations but not cytokine profiles differentiate adult-onset Still's disease and sepsis

M Rau, M Schiller, S Krienke, P Heyder… - The Journal of …, 2010 - jrheum.org
Objective. To analyze clinical manifestations, serum ferritin, and serum cytokine levels in
patients with adult-onset Still's disease (AOSD) or bacterial sepsis and to evaluate their …

Combination of C‐reactive protein, procalcitonin, IL‐6, IL‐8, and IL‐10 for early diagnosis of hyperinflammatory state and organ dysfunction in pediatric sepsis

G Zeng, D Chen, R Zhou, X Zhao, C Ye… - Journal of clinical …, 2022 - Wiley Online Library
Background Although early diagnosis and management are critical for prognosis of pediatric
sepsis, there are no specific diagnostic biomarkers for the hyperinflammatory state and …

Efficacy of coupled plasma filtration adsorption (CPFA) in patients with septic shock: a multicenter randomised controlled clinical trial

S Livigni, G Bertolini, C Rossi, F Ferrari, M Giardino… - BMJ open, 2014 - bmjopen.bmj.com
Objectives Coupled plasma filtration adsorption (CPFA, Bellco, Italy), to remove
inflammatory mediators from blood, has been proposed as a novel treatment for septic …

[HTML][HTML] Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis

S Soni, MD Martens, S Takahara, HL Silver… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Aims Sepsis is a life-threatening condition of organ dysfunction caused by dysregulated
inflammation which predisposes patients to developing cardiovascular disease. The ketone …

[HTML][HTML] Pathophysiologic mechanisms in septic shock

EG King, GJ Bauzá, JR Mella, DG Remick - Laboratory investigation, 2014 - nature.com
The systemic inflammatory response that occurs in the septic patient as a result of an
infectious insult affects multiple organs and systems, causing numerous physiological …

Anti-inflammation activity of exopolysaccharides produced by a medicinal fungus Cordyceps sinensis Cs-HK1 in cell and animal models

LQ Li, AX Song, JY Yin, KC Siu, WT Wong… - International journal of …, 2020 - Elsevier
This study was to assess the anti-inflammatory potential of exopolysaccharide (EPS)
produced by a medicinal fungus Cordyceps sinensis Cs-HK1. The EPS was isolated from …