Objective There is growing evidence that reduced cortical thickness has been considered to
be a central abnormality in schizophrenia. Brain imaging studies have demonstrated that the …

Background Early diagnosis of adolescent psychiatric disorder is crucial for early
intervention. However, there is extensive comorbidity between affective and psychotic …

Background Psychotic symptoms occur in a majority of schizophrenia patients, and in
approximately 50% of all Parkinson's disease (PD) patients. Altered grey matter (GM) …

Schizophrenia manifests as loss of brain volume in specific areas in a progressive nature
and an important question concerns whether long-term treatment with medications …

Neuroimaging studies have documented morphometric brain abnormalities in
schizophrenia, but less is known about them in individuals at clinical high-risk for psychosis …

and subcortical GM) into orthogonal space, with only the important features that explained
the greatest proportion of variance in regressing observers retained [7]. Unlike traditional …

The emergence of the psychosis spectrum (PS; subclinical psychosis-related symptoms)
during late childhood and adolescence (ie, youth) coincides with a period of dynamic …

The considerable variation in the spatial distribution of cortical thickness changes has been
used to parse heterogeneity in schizophrenia. We aimed to recover a 'cortical …

Background vite Ggrey matter (GM) reduction is a consistent observation in established late
stages of schizophrenia, but patients in the untreated early stages of illness display an …

Research has found strong evidence for common and distinct morphometric brain
abnormality profiles in non-affective psychosis (NAff-P) and affective psychosis (Aff-P). Due …